Uridine | PharmaUridine™

Properties: Uridine is one of the fundamental compounds that play an important role in genetics. To put it shortly, it takes part in the processing of information stored in the cells. Functionally, It is a component of RNA acid which is responsible mainly for copying the strings of DNA code. But one could ask a simple question – why would we want to supplement it? Does it have any effects on the brain? As it turns out, uridine’s function is not limited to genetics. As a supplement, it benefits the nervous system, and therefore it is a material used in neuroregulation.

This compound has a wide spectrum of effects, because it influences multiple important processes in the brain. Firstly, it supports the optimal information processing in individual nerve cells. Secondly, it increases the amount of pathways between existing neurons and accelerates the formation of new brain cells. How does that impact our everyday life? Well, the information transmission between neurons becomes faster, and so does our thinking. Apart from that, more connections between neurons increase the capacity of memory. Thus, uridine supplementation directly benefits our cognitive performance: the mind gets brighter and its ability to store and recall memories improves. 

There is one more feature of uridine that is really worth mentioning. Its regular supplementation leads to enhanced psychological wellness. This compound modulates the secretion of dopamine, the neurotransmitter responsible for experiencing pleasure and motivation. These features make uridine an excellent supplement, as it stimulates the brain, improves cognitive performance, and boosts motivation. Additionally, it supports the health of the heart and the liver. Therefore, it positively impacts the general health and accelerates the regeneration of the organism.

Occurrence: Uridine occurs naturally in the human organism. It is synthesized in the liver as a uridine monophosphate (UMP). In the form of RNA it is also present in food. Animal products that contain uridine include: beef liver, pork liver, and fish. Plant-based products such as: baker’s yeast, mushrooms (boletus, common mushroom), broccoli, oats, Chinese cabbage, spinach, cauliflower, parsley or tomatoes are also rich sources of uridine.

Biochemistry: Uridine (uridine nucleoside) is an organic chemical compound classified as nucleoside. In nature it is produced as uridine monophosphate (UMP). Next to adenosine, guanosine and cytidine it is one of the fundamental components of the ribonucleic acid (RNA). It is well absorbed from the digestive tract and highly water-soluble. Uridine can cross the blood-brain barrier efficiently, therefore it is often used in order to improve the functioning of the brain. It is also a substrate in phosphatidylcholine (PC) and glycogen synthesis. Moreover, it plays a role in carbohydrates metabolism.

Fun fact: Beer can be an excellent source of uridine. However, the density of this compound varies depending on the type of beer. One jar of beer can contain between 40 and 80 mg of uridine.