GLA extract 20% | Omega-6 from borage

Properties: Borage contains significant amounts of gamma-linolenic acid (GLA), and because of that it is considered the best source of this compound. GLA found in the seeds of borage provides comprehensive support for the entire organism. It works on many levels, supporting major body functions, which makes it one the most important, though often underestimated, omega-6 fatty acids. It shows anti-inflammatory properties but also relieves pain. That is why for centuries herbal extracts with high GLA content have been used as a remedy for joint disorders and other ailments associated with chronic inflammation. Gamma-linolenic acid counteracts neurodegenerative changes, and plays a significant role in the nervous system as it regulates signal transmission within neurons. 

Moreover, GLA helps to speed up metabolism and improve management of body fat. This compound lowers cholesterol and triglyceride levels in the blood. Thanks to these properties, it facilitates weight reduction. As it has a beneficial effect on the condition of blood vessels, it might be helpful for prevention of cardiovascular diseases, including atherosclerosis. Besides that, it is worth mentioning that GLA is potentially able to regulate the endocrine functions in women. Studies suggest that a deficiency of this omega-6 acid can be associated with a higher frequency of PMS and menopause symptoms, therefore leading to an increase of skin lesions, nervousness or ailments related to digestion. Simultaneously, it has been shown that increasing GLA levels with supplementation can be an important factor reducing these symptoms. And since we mentioned skin, let’s note that gamma-linolenic acid occurs in the lipids that build skin cell membranes, so it is an excellent support for skin condition and appearance. After all, there is a reason why this compound is used as an ingredient of many skin care products. Not only does it help to take care of proper hydration, but also relieves acne symptoms thanks to its anti-inflammatory properties. With GLA the skin is able to maintain its natural glow and a healthy look.

Occurrence: Gamma-linolenic acid (GLA) is naturally produced in the human body, but not always in sufficient amounts. It depends primarily on the activity of the enzyme D6D, which might be impaired in some people. The most valuable sources of GLA include extracts from seeds of borage, evening primrose, black currant or hemp. This compound is also present in spirulina.

Biochemistry: Gamma-linolenic acid (GLA) belongs to the group of omega-6 polyunsaturated fatty acids. In the body, it is synthesized from linoleic acid (LA) with the participation of D6D enzyme, however, usually in low amounts. Therefore, it should be supplied with other omega-6 acids as part of a balanced diet. Vitamins B6, E and C, as well as zinc and magnesium promote proper production of this acid. 

Due to metabolic changes, GLA is converted to dihomo-gamma-linolenic acid (DGLA), which occurs in lipids found in the epidermis. As a result of DGLA oxidation, prostaglandin E1 (PGE1) is produced. PGE1 shows great anti-inflammatory and anticoagulant properties. This compound also helps to take care of the cardiovascular system, as it regulates blood pressure. In addition, it is crucial for the proper functioning of the immune system and shows analgesic effects. It has been proven that balanced GLA activity is particularly important for impulse transmission in nerves and contributes to the prevention of neurodegenerative disorders. It also has a beneficial effect on the lipid profile and insulin sensitivity of the cells.

Omega-6 acids (which include GLA) as well as omega-3 and omega-9 acids belong to the group of polyunsaturated fatty acids. Their molecules have a similar, very complex structure. However, they are distinguished, depending on where the double bond occurs in their carbon chain. When it is located at the sixth carbon atom from the end, the compound belongs to the omega-6 group. And if the double bond occurs at the third or ninth carbon atom, the compound is considered omega-3 or omega-9, respectively.

Fun fact: Borage is one of the best sources of GLA. The systematic name of this plant (Borago officinalis) comes from the Latin word burra. It means “shaggy cloth” and refers to the plant’s hairy leaves.