GLA Omega-6

GLA is one of the key omega-6 fatty acids, which is particularly effective in alleviating chronic inflammation. This compound regulates lipid metabolism, making it easier to maintain proper cholesterol levels. It also shows a beneficial effect on the skin condition, providing it with better hydration and healthy appearance. GLA has been proven to help with the symptoms of PMS and menopause.

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GLA extract 20% | Omega-6 from borage

Properties: Borage contains significant amounts of gamma-linolenic acid (GLA), and because of that it is considered the best source of this compound. GLA found in the seeds of borage provides comprehensive support for the entire organism. It works on many levels, supporting major body functions, which makes it one the most important, though often underestimated, omega-6 fatty acids. It shows anti-inflammatory properties but also relieves pain. That is why for centuries herbal extracts with high GLA content have been used as a remedy for joint disorders and other ailments associated with chronic inflammation. Gamma-linolenic acid counteracts neurodegenerative changes, and plays a significant role in the nervous system as it regulates signal transmission within neurons. 

Moreover, GLA helps to speed up metabolism and improve management of body fat. This compound lowers cholesterol and triglyceride levels in the blood. Thanks to these properties, it facilitates weight reduction. As it has a beneficial effect on the condition of blood vessels, it might be helpful for prevention of cardiovascular diseases, including atherosclerosis. Besides that, it is worth mentioning that GLA is potentially able to regulate the endocrine functions in women. Studies suggest that a deficiency of this omega-6 acid can be associated with a higher frequency of PMS and menopause symptoms, therefore leading to an increase of skin lesions, nervousness or ailments related to digestion. Simultaneously, it has been shown that increasing GLA levels with supplementation can be an important factor reducing these symptoms. And since we mentioned skin, let’s note that gamma-linolenic acid occurs in the lipids that build skin cell membranes, so it is an excellent support for skin condition and appearance. After all, there is a reason why this compound is used as an ingredient of many skin care products. Not only does it help to take care of proper hydration, but also relieves acne symptoms thanks to its anti-inflammatory properties. With GLA the skin is able to maintain its natural glow and a healthy look.

Occurrence: Gamma-linolenic acid (GLA) is naturally produced in the human body, but not always in sufficient amounts. It depends primarily on the activity of the enzyme D6D, which might be impaired in some people. The most valuable sources of GLA include extracts from seeds of borage, evening primrose, black currant or hemp. This compound is also present in spirulina.

Biochemistry: Gamma-linolenic acid (GLA) belongs to the group of omega-6 polyunsaturated fatty acids. In the body, it is synthesized from linoleic acid (LA) with the participation of D6D enzyme, however, usually in low amounts. Therefore, it should be supplied with other omega-6 acids as part of a balanced diet. Vitamins B6, E and C, as well as zinc and magnesium promote proper production of this acid. 

Due to metabolic changes, GLA is converted to dihomo-gamma-linolenic acid (DGLA), which occurs in lipids found in the epidermis. As a result of DGLA oxidation, prostaglandin E1 (PGE1) is produced. PGE1 shows great anti-inflammatory and anticoagulant properties. This compound also helps to take care of the cardiovascular system, as it regulates blood pressure. In addition, it is crucial for the proper functioning of the immune system and shows analgesic effects. It has been proven that balanced GLA activity is particularly important for impulse transmission in nerves and contributes to the prevention of neurodegenerative disorders. It also has a beneficial effect on the lipid profile and insulin sensitivity of the cells.

Omega-6 acids (which include GLA) as well as omega-3 and omega-9 acids belong to the group of polyunsaturated fatty acids. Their molecules have a similar, very complex structure. However, they are distinguished, depending on where the double bond occurs in their carbon chain. When it is located at the sixth carbon atom from the end, the compound belongs to the omega-6 group. And if the double bond occurs at the third or ninth carbon atom, the compound is considered omega-3 or omega-9, respectively.

Fun fact: Borage is one of the best sources of GLA. The systematic name of this plant (Borago officinalis) comes from the Latin word burra. It means “shaggy cloth” and refers to the plant’s hairy leaves.

How does GLA extract 20% | Omega-6 from borage work?

Anti-inflammatory effect: It has been noted even years ago that products with gamma-linolenic acid are able to alleviate symptoms of chronic inflammation. Studies have shown that GLA regulates levels of proinflammatory cytokines. During clinical trials, this compound has been proven to provide valuable support in diseases such as arthritis and rheumatism, as it reduces inflammation and relieves pain. Its potential in the treatment of neuropathy is also being investigated. Indeed, it is believed that GLA may reduce nerve damage.

Supports a healthy diet: Ending a weight loss diet and returning to one’s typical eating habits is often a critical moment when weight gain resumes. There are reports that GLA can prevent this yo-yo effect to some extent. This is because it has the ability to boost metabolism and to modify the way energy is stored within the body. Additionally, it helps to control plasma cholesterol and triglyceride levels. During a small critical trial involving dozens of participants, it has been proven that a formula with GLA can be useful in significant weight reduction.

Relieves PMS and menopause symptoms: Research indicates that there might be correlation between GLA deficiency in women and a significant increase of premenstrual syndrome (PMS) and menopause symptoms. Supplementation with this compound has been proven to alleviate PMS symptoms such as swelling and soreness of the breasts, acne, irritability or bloating. It also reduces the number of hot flashes and the intensity of night sweats during menopause. What is more, it increases bone density and promotes the prevention of osteoporosis that women in the postmenopausal period are particularly vulnerable to. Researchers speculate that progesterone-like activity of GLA might be a source of these effects.

Improves skin condition: Gamma-linolenic acid benefits the skin – whether it’s applied topically or taken by mouth. It has been proven to support proper skin hydration and firmness. It prevents excessive peeling, and relieves symptoms such as redness, itching, dryness or hypersensitivity. It also helps to fight acne, mainly due to anti-inflammatory effects and the ability to inhibit the growth of certain bacteria. In that regard, it is also important that GLA can prevent the conversion of testosterone into dihydrotestosterone (DHT), which promotes acne formation. Scientists speculate that this mechanism may also counteract excessive hair loss.

GLA extract 20% | Omega-6 from borage product specification

 

TYPE OF PRODUCT:
  • powdered raw ingredient
STANDARDIZATION:
  • Borage | Borago officinalis seed extract (20% gamma-linolenic acid)
MEASURING:
  • 1.0 ml PET spoon containing 500 – 600 mg of extract (depending on the batch)
PACKAGING:
  • airtight ALU-PET foil bag
  • desiccant packet Tyvek™ Microbag
INTENDED USE:
  • nutrition
  • neuroregulation
  • natural medicine
  • product manufacturing
  • research
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

How to use GLA extract 20% | Omega-6 from borage?

 

RECOMMENDED SERVING:
  • 250 – 500 mg
SERVINGS PER DAY:
  • 1 – 3
BEST ABSORPTION:
  • with food
WHEN TO USE:
  • during the day / before bedtime
OPTIMAL CYCLE DURATION:
  • 12 weeks of using – 4 weeks of break

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.