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Acetyl-L-carnitine (ALCAR) is an amino acid similar to the popular L-carnitine. It is, however, more absorbable and exhibits more properties. Not only does it improve physical capacity and muscle strength, but mainly it supports the nervous system. Thanks to ALCAR, the brain can work efficiently, the focus is more stable and it’s easier to process new information.

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ALCAR | Acetyl-L-carnitine

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ALCAR | Acetyl-L-carnitine

Properties: ALCAR is a derivative of L-carnitine which is widely used by athletes as the support for muscle performance. It reduces muscle soreness after a demanding workout. Acetyl form of L-carnitine – ALCAR has the broader spectrum of properties and is more easily absorbed in the gastrointestinal tract. It significantly increases neuronal activity and it takes part in the production of acetylcholine. Therefore, the energy level is noticeably increased. What is more, ALCAR makes it easier to focus and helps to assimilate new information. Additionally, it protects neuron cells’ mitochondria from oxidative stress. Thus, ALCAR has a beneficial effect on neurons, their number and general condition. Mitochondria, the so-called energy factories of the cells, are exposed and vulnerable to many harmful factors. By improving the detoxification process, ALCAR eliminates excessive toxins and fatty acids from the cells. In addition, it “catches” free radicals. ALCAR helps mitochondria and the whole nervous system to function properly. This way, this complex activity of acetyl-L-carnitine allows us to exercise for a longer period of time and to work out more intensively. Additionally, it improves mental capacity and the general state of well-being.

Occurrence: ALCAR occurs in the human body naturally and is produced in every cell by mitochondria –  cell energy sources. In order to maintain an appropriate ALCAR level in the body, supplementation is often needed. Its main natural sources are products of animal origin, especially meat: beef, chicken and fish.

Biochemistry: Acetyl-L-carnitine (ALCAR) is an organic chemical compound belonging to the group of amino acids. It’s the source of L-carnitine – an amino acid naturally occurring in animal tissues. In comparison to “simple” L-carnitine, ALCAR has higher bioavailability and has a stronger impact on the central nervous system. Its maximal concentration in blood plasma occurs 3 hours after taking it. Additionally, it readily crosses the blood-brain barrier. In the central nervous system, ALCAR is the donor of the acetyl group which is the substrate for acetylcholine, glutamate and GABA production. It also takes part in the production of myelin sheaths as it stimulates creating lipids that surround neurons. After the attachment of acetyl group, ALCAR is converted to carnitine, which is engaged in fatty acid metabolism. ALCAR alone is not responsible for those processes.

Fun fact: Acetyl-L-carnitine is the acetyl ester of L-carnitine that was first discovered in 1905 by Gulewitsch and Krimberg. It was found in the skeletal muscle tissue. That is the reason why  its name originates from the Latin word caro, carnis meaning “meat”. Initially L-carnitine was classified as one of the B vitamins but currently it is considered to be a compound similar to vitamins.

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

ALCAR | Acetyl-L-carnitine benefits

Improves memory and cognitive functions: In the course of many scientific studies scientists have noticed significant correlation between acetyl-L-carnitine supplementation and the uptake of acetylcholine by the nerve cells. It has been proven that this mechanism allows an increased synthesis of acetylcholine – a neurotransmitter responsible for the rate of information processing. What is more, ALCAR stimulates release of dopamine – a hormone that regulates energy and motivation levels. ALCAR also increases the concentration of dopamine receptors. Due to the acetylcholine and dopamine enhanced activity, acetyl-L-carnitine has a positive impact on memory, concentration and learning process.

Increases the energy level:  The results of scientific research indicate that acetyl-L-carnitine increases metabolism intensity in the brain tissue by up to 20%, while the glucose intake by nerve cells is elevated by 50%. The biggest changes are observed within the hippocampus and in other brain areas. It has been proven that this amino acid causes a greater release of dopamine and a significant increase in the concentration of receptors for this neurotransmitter. These effects lead to better neuron performance and an increased energy level. Clinical trials proved that ALCAR effectively mitigates symptoms of chronic fatigue like decreased energy level or the lack of motivation. Moreover, this compound is better tolerated than those traditionally used. There was also a limited amount of side effects observed.

Supports the nervous system: ALCAR exerts neuroprotective effect on nerve cells. That has been revealed by both in vitro studies and experiments with animal models. It supports activity of antioxidants naturally occurring in neurons by preventing them from dropping. Thus, it protects nerve cells from the harmful free radicals. ALCAR’s ability to stimulate mitochondria activity in the nerve cells is also important. In addition, acetyl-L-carnitine beneficially affects the condition of cells forming myelin sheaths. Myelin protects and provides nutrients to axons in the central and peripheral nervous systems. ALCAR’s activity improves myelin sheath regeneration after the injury.

Supports physical performance: Acetyl-L-carnitine increases the intensity of metabolism in the body cells, including muscle fibers. It leads to increased muscle efficiency. Additionally, ALCAR has the ability to reduce the amount of lactic acid which is produced during the physical training. Thus, it prevents muscle tissue from the damage after the workout. ALCAR affects the level of cardiolipin – the compound that occurs in heart muscle cells and has an important role in the respiratory chain reactions. The content of cardiolipin declines with age, but ALCAR has the ability to restore its level, which is important for heart fitness. That way, acetyl-L-carnitine improves overall physical performance.

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

ALCAR | Acetyl-L-carnitine specification

PRODUCT TYPE:
  • powdered preparation
STANDARDIZATION:
  • pure acetyl-L-carnitine HCL (>99%)
MEASURING TOOL:
  • 0.50 – 1.00 ml PET spoon containing 300 – 750 mg of ALCAR (depending on the batch, information on the label)
PACKAGING:
  • airtight ALU-PET foil bag
  • desiccant packet Tyvek™ Microbag
INTENDED USE:
  • scientific research, dietetics, natural medicine, neuroregulation, production of supplements and cosmetics
LEGAL STATUS:
  • The raw material is approved for trading in the EU
ATTACHMENTS:

 
Certificate of Analysis

The specification above contains a description and composition of all available variants of a given product or set. Depending on the batch of a given raw material or set, some information may differ slightly from the description on the label. The product photo is for illustrative purposes only.

Under European Union law, this product or some of its ingredients may be classified as not intended for consumption (so-called novel foods, nutraceuticals, nootropic compounds). Before purchasing, please familiarise yourself with the legal regulations regarding the legality of using this product or its ingredients in the country of destination.

ALCAR | Acetyl-L-carnitine usage

OPTIMAL SERVING SIZE:
  • 300 – 600 mg
OPTIMAL SERVINGS AMOUNT:
  • 1 – 3 pre day
OPTIMAL ABSORPTION:
  • without food
OPTIMAL USAGE:
  • during the day / before activity
OPTIMAL CYCLE DURATION:
  • 6 weeks of using – 2 weeks of break

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

ALCAR | Acetyl-L-carnitine stacking

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The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

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