Emoksypina Mexidol
Emoksypina Mexidol

Emoxypine is an innovative variation of vitamin B6 with nootropic properties. It shows strong antioxidant effects that help to protect bodily cells from damage. This compound supports intellectual performance and cognitive functions but also has a positive influence on mood. It might be quite effective during physical effort as it improves circulation and stimulates recovery processes.

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Emoxypine | Mexidol™

Properties: Emoxypine is a not quite popular, yet really interesting compound that exhibits potential as a nootropic. Thanks to the dedication of scientists researching vitamin B6 and its effects, it was possible to obtain a completely new form that shares many properties with pyridoxine but also induces other unique effects. Primarily, it can support functioning of the nervous system and improve general condition of the organism.

As an effective antioxidant, emoxypine protects neurons from damage caused by reactive oxygen species. It has been proven that it stimulates production of natural antioxidants, e.g. superoxide dismutase, preventing oxidation of fatty acids that build cellular membranes of the nerve cells. Besides that, it facilitates blood flow in the vessels that supply the brain with oxygen and other essential nutrients. Because of that, neurons can be prepared for more efficient and prolonged work. Research also indicates that this new derivative of vitamin B6 has a beneficial influence on the activity of neurotransmitters that regulate transmission of signals between nerve cells. Emoxypine increases sensitivity of acetylcholine receptors. Note that acetylcholine is essential for cognitive functions and efficient information processing. Simultaneously, emoxypine reduces breakdown of dopamine that is particularly important for working memory and focus.

Dopamine actually has many important functions in our nervous system. High amounts of this compound are released during stimulation of the reward system – a “brain center” of motivation and feelings such as pleasure or satisfaction. It is worth noting that this enhanced version of vitamin B6 helps to improve the activity of this as well as other brain chemicals that are crucial for well-being and stress resilience. It can influence GABA receptors, making it easier for proper molecules to attach. Additionally, this substance inhibits the activity of MAO – an enzyme capable of neutralizing serotonin – so this neurotransmitter is able to remain in the synapses for a longer time and have a stronger effect on the nervous system. Balanced activity of all these compounds is necessary to enjoy a stable and more relaxed mind, even in challenging situations.

But emoxypine has more to offer besides improving efficiency of the brain. Scientists emphasize that this derivative of pyridoxine can even support physical performance. Thanks to vasodilatory properties, it facilitates transport of essential nutrients to muscle cells that are able to obtain more energy. What is more, it has been shown that this compound can mitigate the effects of muscle soreness which, as likely every physically active person knows, can be very inconvenient. Let’s add the fact that emoxypine may lower total cholesterol level, changing its proportions in favor of a “good” cholesterol HDL, but also reduce the risk of thrombosis and improve blood flow in the vessels. So, there it is – a valuable nootropic version of vitamin B6 that provides benefits for the organism on many levels.

Occurrence: Emoxypine was developed in the 1970s by the research group from the Institute of Pharmacology at the russian Academy of Medical Sciences and the National Scientific Center of Bioactive Substances Safety. Currently, it is produced by laboratories all over the world.

Biochemistry: Emoxypine is a derivative of pyridoxine (vitamin B6). Its full chemical name is 2-ethyl-6-methyl-3-hydroxypyridine.

Fun fact: Emoxypine that is available on the market, quite often occurs as a succinate salt. Thanks to health-promoting properties of succinate, this version has a slightly wider spectrum of effects than a pure form.

How does Emoxypine | Mexidol™ work?

Supports the nervous system: Emoxypine has a great influence on physical as well as intellectual performance. Thanks to research studies, it has been shown that it helps to maintain a good condition of the central nervous system. In this context, its strong antioxidant effects play an important role. This newer form of vitamin B6 protects neuronal cell membranes from oxidation of fatty acids that are necessary to build them. Moreover, it can stabilize these membranes, increasing the amount of phospholipids, such as phosphatidylserine or phosphatidylinositol, contained in them. At the same time, emoxypine improves blood flow in the vessels that supply the brain, so more oxygen can reach this precious organ and support its functioning. This substance can also influence the activity of neurotransmitters that are important in terms of cognitive functions: dopamine and acetylcholine. It is able to inhibit breakdown of dopamine, allowing its molecules to stay in the synapses, and to increase sensitivity of acetylcholine receptors (so the molecules of this brain chemical can induce more pronounced effects in the brain). Essentially, dopamine regulates levels of energy and motivation, while acetylcholine controls the speed of information processing that occurs in the brain. The proper activity of both these compounds is crucial for learning abilities and attention.

Supports a good mood: Research indicates that emoxypine can be effective in reducing nervous tension and improving general mood. Scientists suppose that these results are based on its influence on the nervous system. Most likely, it facilitates attaching specific molecules to the receptors of GABA. We should also mention that emoxypine may reduce the activity of MAO – an enzyme that catalyzes breakdown of dopamine and serotonin. GABA is the main inhibitory neurotransmitter that regulates nervous tension and stress resilience. Dopamine is usually secreted in response to the activation of the brain’s reward system and induces feelings of pleasure. Serotonin, on the other hand, helps to maintain mental comfort. With a higher activity of all these compounds it should be easier to enjoy a positive outlook, even in the face of demanding situations. The results of studies suggest that this newer version of pyridoxine may also be of use when struggling with insomnia that very often is a result of prolonged stress. However, what’s really important, is the fact that even though this compound helps to calm nerves and supports sleep, it does not induce sedative effects by itself. Research also suggests that emoxypine may be useful in therapies aimed at reducing intake of alcohol or other drugs. There is still ongoing research on that subject.

Improves physical endurance: There are studies proving that emoxypine is a substance that helps with adapting to tough circumstances. It improves circulation and thus more oxygen and nutrients can be delivered to muscles. This compound has a positive effect on the body, particularly in situations when oxygen supply is reduced, which may happen during more demanding trainings. That way, emoxypine makes it slightly easier to engage in longer and more intense workout routines. Besides that, it may also counteract muscle soreness, making recovery more efficient. What is more, nootropic properties of this compound might be beneficial in sports that require a lot of analytical thinking. All these effects make this substance a reasonable choice for people who enjoy an active lifestyle.

Supports the cardiovascular system: Results of research studies show that emoxypine has a particularly positive influence on the heart and the condition of blood vessels. There is also evidence that this compound prevents excessive coagulation and improves blood flow, even in coronary vessels that provide the heart with oxygen and essential nutrients. In addition to that, emoxypine regulates lipid profile – lowering cholesterol level in general, while promoting concentration of its “good” type – high density lipoprotein (HDL). Research indicates that this form of vitamin B6 can protect tissues – including the heart muscle – from the effects of temporary inadequate blood supply. Surely, antioxidant properties of this substance are of great importance in that regard. As well as the fact that it supports proper functioning of mitochondria – structures that produce ATP, the main energy carrier in cells. All these factors help to keep the circulatory system in a good condition.

Emoxypine | Mexidol™ product specification

 

TYPE OF PRODUCT:
  • powdered raw ingredient
STANDARDIZATION:
  • emoxypine succinate (>99%)
MEASURING:
  • 0.30 ml stainless steel spoon containing 150 – 250 mg of emoxypine (depending on the batch)
PACKAGING:
  • airtight ALU-PET foil bag
  • desiccant packet Tyvek™ Microbag
INTENDED USE:
  • nutrition
  • neuroregulation
  • natural medicine
  • product manufacturing
  • research
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

How to use Emoxypine | Mexidol™?

 

RECOMMENDED SERVING:
  • 150 – 300 mg
SERVINGS PER DAY:
  • 1 – 3
BEST ABSORPTION:
  • without food
WHEN TO USE:
  • during the day / before bedtime
OPTIMAL CYCLE DURATION:
  • 6 weeks of using – 2 weeks of break

How to stack Emoxypine | Mexidol™?

To support the nervous system:
CDP-Choline | Citicoline
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CDP-Choline Citicoline

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Inositol | Myo-inositol
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Alpha-GPC 50% | AlphaCholine™
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Alpha-GPC

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Phosphatidylcholine 20% | Helianthus annuus
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To improve well-being:
Sulbutiamine | NeuroThiamine™
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NALT | NeuroTyrosine™
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SAM-e | S-adenosyl methionine
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Theacrine | PharmaTea™
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To support physical endurance:
ALCAR | Acetyl-L-carnitine
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ALCAR Acetyl-L-Carnitine

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NALT | NeuroTyrosine™
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Coenzyme Q10 | Ubiquinone
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Coenzyme Q10 Ubiquinone

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Caffeine | Anhydrous caffeine
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caffeine

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To support circulation:
NAC | NeuroCysteine™
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TMG | Betaine anhydrous
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L-Taurine | PharmaTaurine™
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Inositol | Myo-inositol
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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.