NEURO-BOX™ GABA is the most comprehensive remedy for high deficits of GABA. This unique composition of amino acids, herbs and vitamins helps to regain inner balance. It is able to increase stress resilience and improve sleeping comfort. And in the morning, thanks to proper GABA activity, it should be easier to wake up feeling physically and mentally refreshed.
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NEURO-BOX™ GABA formula properties
NEURO-BOX™ GABA is the most efficient solution for high GABA deficits. When GABA level is significantly lowered, we might experience frequent states of irritation, nervousness and anxiety. Common symptoms often include mood swings and agitation. Issues regarding GABA activity might also be related to memory and attention problems. People with low levels of this neurotransmitter usually have trouble dealing with stressful situations, have low self-esteem and might feel depressed.
- NEURO-GABA™ Balance: Balancing Formula is based on chemical compounds that can be used as a foundation of the whole neuroregulation process. It contains precursors and cofactors necessary for the proper synthesis of GABA. They also affect GABA receptors, further improving the activity of this neurotransmitter. However, when those substances are not supplied regularly, GABA activity might deteriorate. With our unique formula it is possible to support processes that will lead to an improvement of that activity.
- NEURO-GABA™ Active: Activating Formula is a unique composition of herbal extracts that have been proven to support GABA activity. They contain high amounts of biologically active compounds that stimulate natural processes that occur in the organism. This way, our formula intensifies the production of GABA and sensitizes receptors of this neurotransmitter to make it more efficient. The Activating Formula helps to optimally use the elements provided with the Balancing Formula and thus supports the process of neuroregulation.
NEURO-BOX™ GABA can be a part of an individualized therapeutic protocol prepared during Neurophysiological Consultation.
Ingredients of NEURO-GABA™ Balance (proprietary formula):
GABA | Gamma-aminobutyric acid
GABA is an amino acid that acts as a main inhibitory neurotransmitter in the nervous system. The proper level of GABA in the organism provides a state of relaxation as this substance can effectively reduce transmission between neurons and, hence, calm down the nervous system. For the same reason it has a great effect on mood and sleep comfort. During sleep it supports regeneration because of increased growth hormone secretion. That way, it affects muscle fiber recovery. Usually, GABA supplementation does not affect the brain directly since it does not cross the blood-brain barrier. However, this amino acid affects neural transmission by interacting with the gut-brain axis.
L-lysine | PharmaLysine™
Lysine is an essential amino acid - it cannot be synthesized in the human body. Thus, it must be provided with food or supplements. Lysine is one of the most important amino acids that can be used to synthesize proteins, particularly those that build muscles, tendons and bones. What is more, lysine acts as a precursor for carnitine - a compound that regulates the transport of long chain fatty acids to the mitochondria for subsequent process of β-oxidation that leads to the production of energy in the form of ATP. It is worth noting that lysine helps to synthesize different hormones and enzymes but also antibodies used by the immune system to identify and neutralize pathogens. Besides that, it takes part in the production of nucleotides - basic monomeric units that build DNA. Lysine can also regulate the activity of key neurotransmitters, e.g. glutamate that is important in terms of effective learning. It also modulates GABA A receptors and decreases the amount of released cortisol which helps to reduce the intensity of stress reactions.
L-Taurine | PharmaTaurine™
L-taurine is an amino acid with anabolic, nootropic and anxiolytic properties. It is widely used by athletes because it intensifies protein production while reducing degradation of proteins. What is more, l-taurine is an anti-inflammatory and anti-catabolic compound. It also supports regeneration and growth of muscle fibers which provides better physical condition. However, this amino acid does not work on muscles only. It does support the nervous system as well. There is research data about l-taurine’s ability to intensify production of new nerve cells in the hippocampus, which is possible because of activation of stem cells and increase of neuronal progenitor cells. Moreover, l-taurine protects new cells from harmful factors, so they have better longevity. Thanks to this mechanism, this amino acid can stimulate neurogenesis in adults and prevent premature brain aging. By regulating GABAergic and serotonergic systems, it also stabilizes the mood.
L-Theanine | PharmaTheanine™
L-theanine is a natural amino acid considered to be a part of nootropic and compounds that support and protect the nervous system. It can be found in the leaves of common tea (Camellia sinensis) - making up to 3% of dried leaf mass. One of the main properties of L-theanine is the ability to improve stress resilience. This compound inhibits cortisol while stimulating the activity of GABA - a key neurotransmitter that helps to mitigate stress symptoms. Moreover, L-theanine stimulates alpha brain waves that are related to the state known as a “relaxed attention”, typical for activities requiring a high focus, e.g. meditation. Thanks to that, L-theanine makes it easier to concentrate on the task at hand. It also has a beneficial effect on memory because it stimulates the process of neurogenesis during which new neural cells are produced. In dietary supplements L-theanine is often mixed with caffeine because in this composition stimulatory effects of caffeine are more subtle yet more durable with much less side effects such as agitation or anxiety.
Magnesium chelate | BioMagnesium™
Magnesium is a chemical element that belongs to the group of macroelements. It is crucial for the proper functioning of the human organism, especially the central nervous system. It is also an electrolyte and a cofactor in many enzymatic reactions related to metabolism, protein synthesis as well as the production of hormones and neurotransmitters. Magnesium can be found in food products, particularly in cocoa, legumes, buckwheat, hazelnuts or oatmeal.
Vitamin B1 | Thiamine
Vitamin B1 participates in the metabolic processes of energy production and glucose breakdown. It helps to reduce symptoms of fatigue. It is worth mentioning that vitamin B1 takes part in regulation of neurotransmitter activity, particularly glutamate and GABA. This vitamin is also crucial for the production of acetylcholine that facilitates information acquisition and supports intellectual performance.
Vitamin B6 | Pyridoxine
Vitamin B6 is a key compound that supports proper functioning of the central nervous system, particularly in terms of maintaining a positive attitude. It is a cofactor in the production of neurotransmitters, including GABA, dopamine and serotonin. Besides that, vitamin B6 is important for metabolic processes that occur in neurons and protects those cells from premature degeneration. It can be found in food products, such as soy, yeast, chickpeas, starchy vegetables, bananas, fish and meat.
Vitamin B9 | Folic acid
Vitamin B9 is crucial for the proper functioning of the nervous system as it participates in the production of important neurotransmitters, including serotonin and dopamine. It also facilitates detoxification processes that occur in the body by protecting the liver and kidneys. It has been proven that oxidative properties of vitamin B9 make this compound a valuable support for premature aging prevention. It protects the DNA from mutations and thus helps to maintain vitality.
Ingredients of NEURO-GABA™ Active (proprietary formula):
Reishi | Ganoderma lucidum
Ganoderma lucidum, better known as reishi, is a fungus that belongs to the group of adaptogens. It contains beta-glucans that stimulate cells of the immune system that destroy pathogenic microorganisms. What is more, reishi improves the blood flow in coronary arteries and reduces viscosity of blood, which is beneficial in heart attack prevention. What is more, reishi supplementation provides a better mood and reduces stress symptoms. It is possible because this fungus stimulates the activity of GABA - the main inhibitory neurotransmitter. It also influences cognitive functions in a positive way which makes it an effective nootropic supplement as it supports intellectual performance, memory and attention.
Ashwagandha | Withania somnifera
Ashwagandha has been used in Traditional Chinese Medicine for thousands of years. It has strong adaptogenic and nootropic properties, and additionally it helps to regulate activity of key neurotransmitters. It supports GABA and serotonin activity while inhibiting secretion of cortisol - a “stress hormone”. Because of that, Ashwagandha helps to relax and has antidepressant properties. What is more, this herb stimulates acetylcholine activity in the brain and that, in turn, brings improvement of cognitive functions, including attention and memory. Ashwagandha also helps to raise the level of testosterone, which effectively increases libido, facilitates muscle mass gain and makes muscles stronger. At the same time, it strengthens natural immunity and protects neurons from damage.
Lemon balm | Melissa officinalis
Lemon balm is a plant widely known all over the world for its ability to reduce anxiety. The natural compounds found in this herb are ursolic acid and rosmarinic acid. Those substances catalyze the reaction of conversion of L-glutamate to GABA. The other active compounds can modulate the activity of GABA receptors. That is why lemon balm extract helps to reduce tension and other symptoms of stress. Melissa officinalis also helps to fall asleep faster if taken in the evening while providing better regeneration during the sleep - both mental and physical.
Gotu Kola | Centella asiatica
Gotu Kola is an herb that comes straight from Asia. It has an extraordinarily positive influence on the brain condition. Even small amounts of Gotu Kola taken regularly can improve the functioning of the cardiovascular system and keep cognitive abilities at a high level. Research studies prove that this herb can increase blood flow in the brain, but also increase nerve-growth factor expression and slow down the aging processes. Gotu Kola supplementation also stimulates acetylcholine activity providing better memory and focus. At the same time, it improves stress resilience and mood.
Passion flower | Passiflora Incarnata
Passiflora is an herb that comes from the North and Central Americas where it has been used by local Indian tribes for thousands of years. The European colonizers brought passiflora to the Old Continent in the 18th century. This herb has become so popular because it regulates the activity of serotonin, the so-called “happiness hormone”, as well as GABA - a key neurotransmitter responsible for stress resilience that reduces the intensity of emotional reactions. Passiflora supplementation supports better sleep and helps to relax. It also increases libido since active compounds found in this plant improve testosterone production. The most important of those compounds are indole alkaloids and the essential oil which is a composition of 150 different ingredients.
Skullcap | Scutellaria baicalensis
Scutellaria, commonly known as skullcap, is a plant that comes from North-Eastern Asia. In ancient China it has been used for thousands of years as a remedy for infections but also in order to treat ailments of the digestive system, asthma or allergies. Roots of skullcap contain up to 20% of biologically active flavonoids. Skullcap extract primarily supports GABA activity, bringing better sleep and improving stress resilience. It has also been proven that skullcap stimulates the immune system to fight incoming threats such as harmful pathogens but it also shows anti-inflammatory properties. Over time, modern research studies prove the effectiveness of more and more traditional skullcap uses.
Phosphatidylserine | AlphaSerine™
Phosphatidylserine is a compound that naturally occurs in the human organism. It is one of the main phospholipids that build all of the cell membranes. The highest concentration of this substance can be found in the brain, particularly in the cortex and hippocampus, and that is why phosphatidylserine has great influence on the nervous system. Primarily, it improves efficiency of signal transmission between cells and regulates secretion of neurotransmitters as well as hormones. It affects the activity of acetylcholine, dopamine and noradrenaline - the substances that provide better mood, cognitive functions and motivation. Moreover, phosphatidylserine helps to reduce stress symptoms because it inhibits cortisol - the so-called “stress hormone”. In addition, this compound increases the intensity of alpha brain waves, which are associated with relaxation and mood stability.
Piperine | Piper nigrum
Piperine is an active compound that occurs in black pepper - one of the most popular spices used worldwide. It is the piperine that gives pepper its distinctive strong, spicy aroma and taste. This compound can be effectively used to support the nervous system as it significantly increases bioavailability of many other herbal ingredients that do not absorb very well on their own, e.g. curcumine that absorbs 20 times better when mixed with piperine. Besides that, piperine exhibits antioxidant properties which means that it helps to protect cellular structures, including DNA, from harmful effects of free oxygen radicals. Moreover, it might be a good support in weight reduction because it helps to regulate metabolism in fatty cells and stimulates lipid breakdown. In addition to that, piperine shows potential as a nootropic ingredient that supports the nervous system. It inhibits the activity of acetylcholinesterase that breaks down acetylcholine. Hence, the density of this neurotransmitter in synapses is higher. On top of that, piperine increases the level of the brain-derived neurotrophic factor in the hippocampus. In effect, long-term memory and the ability to acquire information is improved.
NEURO-BOX™ GABA formula benefits
Improves stress resilience:
- Balance: Our special Balancing Formula contains substances that support GABA activity in different aspects. There are compounds that facilitate the production of this neurotransmitter, modulators that increase sensitivity of its receptors and those that stimulate their activity. All these substances help to significantly improve GABA effects in the nervous system. After all, this neurotransmitter mitigates the negative symptoms of stress. So, with a proper support for the GABAergic system, it might be easier to regain inner comfort and emotional balance.
- Active: The ingredients of Activating Formula also provide support for GABA activity. They mainly affect the receptors of this neurotransmitter, improving their sensitivity and activating them just like GABA molecules which helps to induce stronger effects. They may also prevent these molecules from breaking down too quickly. In effect, GABA can remain in the synaptic clefts and affect specific neurons for a longer time. All in all, our recipe helps to reduce the activity of the hypothalamic-pituitary-adrenal (HPA) axis that is highly stimulated in response to stressful events. This increased activity of the HPA axis is related to a strong cortisol release that brings most of the negative consequences of stress. The high quality herbal extracts contained in this formula provide scientifically-proven, positive effects on the GABAergic system, promoting relaxation within the body and mind.
Improves sleep quality:
- Balance: Sleeping problems are quite often caused by a prolonged exposure to high stress. In these circumstances, the body might be too tense and the mind too agitated to properly relax and sleep comfortably after a long and tiring day. GABA helps to reduce the intensity of nerve impulses, which is especially important before bedtime when we need to calm down and prepare for a good night’s rest. Thanks to our special formula that significantly improves GABA activity it might be easier to experience a longer and more efficient sleep.
- Active: Activating Formula affects GABA receptors and reduces the breakdown of its molecules, supporting the relaxing and sleep-inducing effects of the Balancing Formula. It is also worth mentioning that our herbal composition is able to increase the activity of another neurotransmitter – serotonin. Both serotonin and GABA are crucial to maintain healthy sleeping patterns and effectively regenerate the body during bedtime. The results of research studies indicate that the ingredients of NEURO-GABA™ Active help to regulate a natural rhythm of sleep and maintain a balance between the REM and NREM phases which is necessary to fully recover and feel refreshed when we wake up.
Supports a good mood:
- Balance: GABA is an important compound that helps to achieve peace of mind. Proper activity of this neurotransmitter is crucial to reduce intensity of stress, lower frequency of mood swings and maintain clarity of thinking, even in tough circumstances. The ingredients of the Balancing Formula are able to improve the concentration of GABA but that’s not all. They also include cofactors that are necessary to produce serotonin and dopamine – two neurotransmitters that induce the feeling of satisfaction and a positive attitude. By stimulating those spheres of neuronal activity, this special formula might improve general well-being.
- Active: Serotonin is commonly known as a “happiness hormone” because of its positive effect on mood. Dopamine, on the other hand, has an important role in the reward system that stimulates feelings of pleasure and satisfaction. Thanks to the ingredients of our Activating Formula, the molecules of those neurotransmitters are broken down at a slower rate, so they can affect specific neurons for a longer time and with better results. And since all of those herbal extracts stimulate the activity of GABA, it might be easier to reduce mood swings and maintain psychological comfort.
Supports memory and attention:
- Balance: Research studies show that the ingredients of the Balancing Formula may be able to improve the condition of the nervous system. They have been proven to intensify the processes of neurogenesis and neuroplasticity that are crucial to produce new nerve cells and create connections between them. They also stimulate the development of myelin sheaths that wrap around the axons and facilitate the transmission of nerve impulses. There is also evidence that some of those ingredients are able to promote the alpha brain waves that are an indicator of a neuronal activity which is typical for a relaxed and aware brain. Besides that, our formula might protect the nervous system from harmful factors, including the buildup of beta-amyloid. All these properties of NEURO-GABA Balance™ may improve intellectual efficiency.
- Active: The ingredients of the Activating Formula stimulate neurogenesis and neuroplasticity as well. They turn out to be particularly beneficial for the brain’s regenerative capacity but also for the ability to acquire new information. By stimulating the activity of various neurotransmitters, including dopamine, acetylcholine and GABA, they bring positive effects in terms of cognitive functions. The first one is important for multitasking – the ability to focus on many different assignments at the same time. Acetylcholine is crucial for concentration and mental operations that involve memory and association of facts. GABA, on the other hand, helps to stabilize focus by reducing nervousness but also facilitates consolidation of long-term memories. All these effects combined help to keep the brain in a good condition and improve its functioning.
Improves physical performance:
- Balance: The Balancing Formula provides a great support for the body. The ingredients found in this composition are able to improve sleeping quality and thus stimulate regeneration that occurs during a good night’s rest. It is during bedtime, when growth hormone – an important compound that stimulates recovery processes – is secreted most intensively. This unique formula intensifies anabolic processes that regulate the production of proteins, including those that build muscle tissue. Simultaneously, it inhibits catabolic reactions that break proteins down. And because our composition is able to stimulate bone mineralization and production of collagen in the joints, it might be beneficial for the skeletal system, making it more durable. All in all, the ingredients of the Balancing Formula promote vitality and longevity.
- Active: The ingredients of the Activating Formula also support regeneration that occurs during sleep. They stimulate anabolic reactions and growth hormone release. Yet, they can also affect other mechanisms. It has been found that some of those natural extracts may facilitate the absorption of nutrients necessary for proper functioning of the whole body. They have a beneficial effect on the heart and improve microcirculation within capillaries. Because of that, every single cell can receive oxygen and nutrients more efficiently. It is worth mentioning that these ingredients protect muscle tissue from damage caused by excessive physical effort and mitigate pain that might be related to that. In sum, the Activating Formula turns out to be a great support for general stamina and effective recovery after training.
NEURO-BOX™ GABA formula specification
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NEURO-BOX™ GABA formula usage
Activating Formula NEURO-GABA™ Active:
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Balancing Formula NEURO-GABA™ Balance:
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INGREDIENTS:
- Ashwagandha | Withania somnifera
- GABA | Gamma-aminobutyric acid
- Gotu Kola | Centella asiatica
- L-lysine | PharmaLysine™
- L-Taurine | PharmaTaurine™
- L-Theanine | PharmaTheanine™
- Lemon balm | Melissa officinalis
- Magnesium chelate | BioMagnesium™
- Passion flower | Passiflora Incarnata
- Phosphatidylserine | AlphaSerine™
- Piperine | Piper nigrum
- Reishi | Ganoderma lucidum
- Skullcap | Scutellaria baicalensis
- Vitamin B1 | Thiamine
- Vitamin B6 | Pyridoxine
- Vitamin B9 | Folic acid
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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.
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