L-Theanine 99% | PharmaTheanine™

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L-theanine is a natural amino acid responsible for most of the health and nootropic properties of green tea. By increasing the activity of GABA, it helps to relax and mitigates the negative consequences of stress. Beyond that, L-theanine effectively supports the learning process as it improves focus and promotes efficient information acquisition.


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L-Theanine 99% | PharmaTheanine™

Properties: L-theanine is a real gem hidden in the leaves of tea, although it can be found in the highest amounts in green tea. This compound exhibits numerous scientifically-proven, health-promoting and nootropic benefits. Some consider it to be a safe natural remedy for stress and anxiety. For others it is a great support for a deep and efficient sleep as it helps to reduce the intensity of emotions, slow down and relax before going to bed.

The main mechanism that makes L-theanine effective for stress resilience is the ability to promote the activity of GABA – a key inhibitory neurotransmitter that, in a way, acts like a tranquilizer for the mind since it helps to cope with stress and reduces the intensity of anxiety. In addition to that, GABA has been proven to improve the ability to acquire new information because, as research suggests, it stimulates alpha brain waves that induce the state of “relaxed awareness”.

What is more, L-theanine can enhance neurogenesis – a process by which new nervous cells are formed. It helps to increase the amount of neurotrophic factors – specialized proteins that have an important role in the production of neurons and connections between the cells because they control cell proliferation and differentiation within the nervous system. Those processes occur particularly intensively in the hippocampus – a brain structure that is responsible for consolidation of memories.

Moreover, it is worth noting that L-theanine is a strong antioxidant. It can effectively reduce the amount of free oxygen radicals that are a completely normal byproduct of metabolic reactions but can become dangerous for the cells and lead to many disorders if not neutralized properly. Because of that, L-theanine protects fragile cellular structures, such as DNA or mitochondria, from damage and thus helps to keep the whole organism in a good condition. 

However, the influence of this active compound on general vitality is even stronger. It might lower blood pressure, especially in stressful situations, but also turns out to be helpful in lowering cholesterol levels. It is pretty obvious that these effects are quite important for the proper functioning of the heart and the whole circulatory system. Besides that, L-theanine reduces the absorption of carbohydrates and fats, helping with body weight control. It will be a great choice for those that would like to improve their stress resilience, quality of sleep and functioning of the nervous system.

Occurrence: L-theanine occurs predominantly in green tea produced from the unfermented leaves of Chinese tea (Camellia sinensis). It can make up to 3% of their dry mass! Moreover, this amino acid can be found in two species related to tea: Japanese camellia (Camellia japonica) and small camellia (Camellia sasanqua). It is also present in an edible mushroom – brown boletus (Xerocomus badius).

Biochemistry: L-theanine (N-acetyl-L-glutamine) is a natural organic compound that belongs to the group of non-protein amino acids. It makes up to 50% of amino acids found in the leaves of green tea. After administration it is absorbed to the bloodstream and easily crosses the brain blood barrier. Its molecules are structurally similar to gamma-aminobutyric acid (GABA). Research evidence proves that L-theanine can interact with and activate GABA-A receptors just like GABA neurotransmitter.

Fun fact: Since the 1960s L-theanine has been commonly added to food products such as: herbal teas and other drinks, chocolates, puddings, jellies, candies, and chewing gums – especially those made in Japan.

How does L-Theanine 99% | PharmaTheanine™ work?

Reduces stress: L-theanine effectively reduces the intensity of stress and helps to stabilize emotional reactions. This natural amino acid stimulates the activity of GABA – the main inhibitory neurotransmitter that is crucial to maintain inner balance, even in stressful situations. As research data suggests, L-theanine is able to increase (even by 20%) the concentration of GABA in the central nervous system. This is the reason why this compound provides calming effects. Those effects are measurable in lower cortisol and immunoglobulin A levels as well as lower activity of salivary alpha-amylase – the reactions that are related to higher stress levels. Besides that, it has been proven that because of the sedative properties L-theanine supports a deep and healthy sleep, extending its duration and quality.

Supports attention: L-theanine has calming effects and helps to relax. However, the sedative properties of this compound do not impair the clarity of mind and cognitive functions. It’s actually the opposite! L-theanine has been proven to enhance intellectual performance. Researchers who investigated the properties of L-theanine noticed an increase in participants’ alpha brain waves just half an hour after administration. Alpha waves are cycles of the brain’s bioelectric activity that oscillate with frequency between 8 to 13 Hz. They are typical for a brain state called “relaxed awareness”. Their presence indicates the brain’s readiness to acquire information and combine it creatively. It has also been proven that L-theanine successfully improves the ability to focus, especially in highly neurotic individuals. Because of those effects, L-theanine might be a good choice for those that need to improve their psychological well-being but also those who want to support cognitive functions.

Neuroprotective properties: L-theanine can effectively protect the nervous system from harmful factors and thus support its proper functioning. It has been established that this amino acid helps to reduce oxidative stress as it is able to eliminate free oxygen radicals. This way, it can reduce the process of cellular degeneration and support a good condition of the neurons. The beneficial effect of L-theanine is also based on the fact that this compound stimulates the activity of neurotrophic factors – molecules that are crucial for the development of neural cells. Moreover, research suggests that L-theanine affects the receptors of glutamate – an important excitatory neurotransmitter whose excessive activity might lead to many neurodegenerative diseases. Thus, by regulating this activity, L-theanine helps to maintain the homeostasis in the whole nervous system.

Supports the cardiovascular system: Apart from nootropic and neuroprotective properties, L-theanine benefits the cardiovascular system too. It normalizes the functioning of the heart and regulates blood pressure. It has also been proven that L-theanine lowers the level of LDL – a cholesterol type that is sometimes considered a “bad” cholesterol because it might build up in the walls of blood vessels. This way, L-theanine helps to keep those vessels in good condition. Furthermore, by reducing fat absorption from nutrients, it decreases the amount of triglycerides and amino acids in the plasma. This feature, in combination with reduced carbohydrates ingestion, helps to keep proper body weight and supports overall vitality.

L-Theanine 99% | PharmaTheanine™ product specification


  • powdered raw ingredient
  • L-theanine >99%, pharmaceutical quality
  • steel measuring tool 0.30 ml ~ 100 mg
  • airtight ALU-PET bag
  • nutrition, neuroregulation, herbal medicine
  • ingredient admitted to trading in the EU and the US

How to use L-Theanine 99% | PharmaTheanine™?


  • 100 – 200 mg
  • 1 – 3
  • without food
  • during the day / before bedtime
  • 12 weeks of using – 4 weeks of break

How to stack L-Theanine 99% | PharmaTheanine™?

To reduce stress level:
To improve attention:
To stimulate neurogenesis:
To improve general health condition:

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.