DMAE Dimethylaminoethanol
DMAE Dimethylaminoethanol

DMAE is an important compound that acts primarily as a substrate to produce acetylcholine, stimulating the synthesis of this neurotransmitter. Research suggests that DMAE can also effectively regulate the secretion of dopamine and serotonin which positively impacts psychological well-being. Besides that, DMAE has antioxidant properties and protects the neurons from harmful factors.

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DMAE | Dimethylaminoethanol

Properties: DMAE is an organic compound, which naturally occurs in food products, particularly fish and other seafood. In the human organism it has a great impact on the synthesis of an important neurotransmitter – acetylcholine. Thanks to this neurotransmitter we are able to acquire new information and maintain concentration. More specifically, DMAE is a great substrate for acetylcholine production, since it crosses the blood-brain barrier easier than choline. On top of that, it has been proven that this compound indirectly intensifies the secretion of acetylcholine, mainly by redirecting the peripheral flow of choline towards the brain. Thus, DMAE is especially indispensable when the choline/acetylcholine demand increases in response to challenging life events such as new projects at work or important exams. It is also a good addition to other supplements designed to upregulate acetylcholine level.

However, the function of DMAE is not limited to intensification of one neurotransmitter production. Research evidence confirmed its beneficial impact on mood and stress resilience. Scientists suppose that this effect is related to DMAE’s influence on dopamine and serotonin production. Additionally, this compound has protective properties that address both the brain and the entire organism. By itself, it is a strong antioxidant. Therefore, it easily neutralizes free radicals. Furthermore, it decreases the level of an adversarial lipid metabolite – lipofuscin, which can damage the nerve cells and cause the formation of so-called “liver spots”. There are also studies that suggest an even wider range of effects that DMAE has on skin condition. In sum, if you care about the health of mind and skin, and you want to maintain them long into elderhood, you might want to consider DMAE supplementation.  

Note that in cosmetics DMAE is used because of its rejuvenating and anti-wrinkle effects. Simultaneously, it exhibits antioxidative properties. Thus, it neutralizes the free radicals and thereby slows down the aging of the skin. These effects combined improve the general skin appearance, restore its healthy look, improve tenderness and smoothness, and last but not least – reduce the amount of wrinkles. Additionally, it relaxes the facial muscles, which leads to the “lifting” effect. For all these reasons DMAE is commonly used in cosmetics dedicated to mature skin, with a firming and brightening effect. Additionally, it efficiently clears any skin discoloration (e.g. freckles, age spots) resulting from the deposition of lipofuscin in the cells.

Occurrence: DMAE can be found in food products. Seafood (e.g. calmars), sardines, anchovies and salmon are some of its richest sources.

Biochemistry: Dimethylaminoethanol (DMAE; deanol) is an organic chemical compound that belongs to the group of amino alcohols (hydroxylamines). Chemically, it is a difunctional molecule, containing both a tertiary amine group and a primary alcohol group. The presence of these functional groups allows obtaining the appropriate derivatives: salts and esters. Due to the -OH group this chemical is highly water-soluble. Structurally, DMAE resembles choline a lot – it has only one extra methyl group. Choline contains three such groups, whereas DMAE – two. However, DMAE crosses the blood-brain barrier more efficiently. In the organism it serves two main functions. Firstly, it works as a precursor of acetylcholine – an excitatory neurotransmitter. Secondly, it is an indirect compound of phosphatidylcholine production – a phospholipid that constructs cellular membranes. Additionally, it has strong antioxidative properties. Thus, it protects the neurons and other body cells from the adversarial influence of free radicals.

Fun fact: DMAE helps to attain lucid dreaming. This compound stimulates and enhances awareness during the REM sleep phase. Moreover, it lowers general demand for sleep and increases the mind’s clarity upon awakening.

How does DMAE | Dimethylaminoethanol work?

Supports learning: Plenty of scientific studies confirmed that DMAE increases the activity of acetylcholine. The scientists suppose that supplementation with this compound decreases the choline metabolism in the peripheral tissues. Simultaneously, the central nervous system begins to exploit it in a more efficient manner. This neurotransmitter is crucial for memory processes. Its optimal levels allow quick acquisition of new information and makes recalling it easier. DMAE intensifies the acetylcholine production, thereby increasing the efficacy of the learning process.

Improves concentration: The role of acetylcholine in the brain can be compared to the function of the accelerator in the car. Its optimal level determines quick information transmission between the nerve cells and allows the attention to focus on one topic of choice. Research evidence proves that DMAE helps to increase acetylcholine levels. Thereby, it supports concentration, also when it is disturbed. As a result, deanol can enhance the perseverance needed to complete tasks that require intense intellectual effort.

Improves mood: An optimal level of acetylcholine is required for proper mind functioning. Yet, this is not the only function of this neurotransmitter. Its balanced activity is crucial for cognitive skills, but also for psychological well-being. Research evidence suggests that regular DMAE supplementation facilitates mood improvement and reduces anxiety. Researchers suppose that the mechanism of these effects has its roots in the DMAE’s ability to increase the activity of dopamine and serotonin too. These neurotransmitters are crucial to maintain high mood and psychological fitness.

Antioxidant effect: It has been proven that deanol has antioxidative effect. In other words, it neutralizes the free radicals. On top of that, this compound has other neuroprotective properties too. Among others, it protects the nervous system from lipofuscin – a metabolic byproduct that builds up in neurons and other body cells as we age, disturbing their functioning. During experiments scientists have observed that DMAE helps to reduce the amount of this toxic waste, thereby preventing premature aging of the organism.

DMAE | Dimethylaminoethanol product specification

 

TYPE OF PRODUCT:
  • powdered raw ingredient
STANDARDIZATION:
  • DMAE bitartrate (>99%)
MEASURING:
  • 1.0 ml PET spoon containing 600 – 750 mg of DMAE (depending on the batch)
PACKAGING:
  • airtight ALU-PET foil bag
  • desiccant packet Tyvek™ Microbag
INTENDED USE:
  • nutrition
  • neuroregulation
  • natural medicine
  • product manufacturing
  • research
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

How to use DMAE | Dimethylaminoethanol?

 

RECOMMENDED SERVING:
  • 400 – 800 mg
SERVINGS PER DAY:
  • 1 – 2
BEST ABSORPTION:
  • without food
WHEN TO USE:
  • in the morning / during the day
OPTIMAL CYCLE DURATION:
  • 6 weeks of using – 2 weeks of break

How to stack DMAE | Dimethylaminoethanol?

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.