Supports positive mood: Serotonin and dopamine are two neurotransmitters particularly involved in the mood regulation. The first one is mainly responsible for psychological comfort, while the second one regulates the level of motivation and pleasure. Research results demonstrate that active compounds found in St. John’s Wort limit the reuptake of serotonin, while those contained in rhodiola inhibit the activity of enzymes responsible for the breakdown of serotonin and dopamine molecules. Therefore, these molecules remain in synaptic clefts longer and stimulate target neurons more effectively. On top of these effects, the extract of St. John’s Wort sensitizes the receptors of the main inhibitory neurotransmitter in the nervous system – GABA – which plays a crucial role in stress resilience and emotional stability. All in all, thanks to these mechanisms the combination of rhodiola and St. John’s Wort helps to improve the mood. Moreover, it boosts the ability to deal with stress, even in tough circumstances.

Improves attention: The extract from rhodiola contains compounds that inhibit the activity of monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) – enzymes that break down dopamine – a neurotransmitter that is responsible for the ability to focus and smoothly move the loci of attention. Therefore, it determines the span of working memory – a cognitive process that is essential for handling multiple tasks at the same time. St. John’s Wort, on the other hand, keeps the molecules of dopamine in synaptic clefts longer, and therefore affects their target receptors more effectively. Extract from this plant also contains compounds with similar properties to MAO inhibitors. Additionally, it upregulates the activity of glutamate – the main excitatory neurotransmitter in the central nervous system which underlies proper information acquisition and processing. The combination of these effects significantly improves the ability to concentrate, supports learning efficiency, and increases motivation. 

Boosts energy level: Dopamine and noradrenaline are two excitatory neurotransmitters involved in managing the level of energy and motivation. Biologically active compounds found in extracts of rhodiola and St. John’s Wort prevent the molecules of these neurotransmitters from premature decomposition and therefore allow them to affect target receptors longer. This is why these herbs boost energy and enhance motivation. Additionally, Hypericum perforatum exhibits properties that optimize the functioning of mitochondria that produce energy which fuels neurons. Because of that, the efficiency of brain cells increases and so does intellectual performance.