RHODIOLA + ST. JOHN’S WORT is a synergistic composition of two plants that exhibit antidepressant and nootropic properties. By regulating serotonin activity, this pair has an excellent influence on the mood. Besides that, it supports concentration and might be helpful in overcoming the tendency to procrastinate. This combination of natural extracts improves intellectual performance and boosts energy.


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RHODIOLA + ST. JOHN’S WORT formula properties

Rhodiola and St. John’s wort are two extremely popular plants that have been used by natural medicine experts for ages. Although they can be used separately with great results, their synergistic combination is definitely worth trying as both herbs enhance their properties. One of the most important benefits is their antidepressant effect. Rhodiola is primarily known as an adaptogen that has been used to improve the functioning of the organism in harsh conditions, e.g. stressful events. St. John’s wort, on the other hand, is one of the most renowned herbs that can be applied to improve general mood. Since these plants activate different mechanisms of action, they complement each other very well. While rhodiola prevents the breakdown of serotonin and dopamine molecules, St. John’s wort inhibits the reuptake of GABA and simultaneously sensitizes the receptor of this neurotransmitter. Taken together, these effects increase the activity of neuromediators responsible for mood stability, stress resilience, as well as satisfaction from task completion. What is more, these plants also have a beneficial influence on physical health: they support functioning of the heart as well as the liver, and facilitate the regulation of cholesterol level in the blood. Noteworthy, this synergistic composition improves intellectual performance and motivation level, mainly via increased dopaminergic activity and enhanced neuronal mitochondria functioning. Last but not least, supplementation with this traditional recipe has a positive impact on memory processes, particularly in terms of working memory which is especially relevant during intense intellectual effort. 

RHODIOLA + ST. JOHN’S WORT is a classical composition of two herbal extracts with a wide spectrum of effects. Because of its antidepressant properties, it works especially well as a support for lowered mood. On the other hand, its effects might be beneficial for people who desire to support general vitality and efficient work of the brain.

Ingredients of Rhodiola BioSynergy™:

Rhodiola rosea
  • root extract 5% salidroside (500 mg / 2 caps.)
Rhodiola is a plant that can be classified as an adaptogen. It comes from Northern and Central Asia but it also grows in mountain regions of Europe and subarctic areas of North America. In traditional medicine of the Far East rhodiola extract has been used as a substance that helps to adapt to demanding and adverse environmental conditions. R. rosea supports immunity, increases physical endurance and reduces stress. Modern research studies prove that rhodiola indeed supports the immune system but also influences the central nervous system. It stimulates neurogenesis - the process of new nerve cell production - which provides better functioning of the mind and supports cognitive functions, including memory and attention.
St. John's wort | Hypericum perforatum
  • herb extract 0.3% hypericin (350 mg / 2 caps.)
Saint John’s Wort is a popular natural resource that has been used for centuries in order to reduce anxiety. It has strong nootropic and antidepressant properties. The active compounds found in this herb intensify ATP production in mitochondria providing more energy for the cells. What is more, they improve stress resistance and bring better mood by stimulating the activity of neurotransmitters - mainly dopamine and serotonin, which is commonly known as a “happiness hormone”. However, St. John’s Wort does not affect the nervous system exclusively. It has great influence on the whole organism as it supports the activity of enzymes present in the liver and helps to regulate cholesterol level in blood. It also strengthens the immune system by fighting the bacteria and viruses that may be harmful to the body.

RHODIOLA + ST. JOHN'S WORT formula benefits

Supports positive mood: Serotonin and dopamine are two neurotransmitters particularly involved in the mood regulation. The first one is mainly responsible for psychological comfort, while the second one regulates the level of motivation and pleasure. Research results demonstrate that active compounds found in St. John’s Wort limit the reuptake of serotonin, while those contained in rhodiola inhibit the activity of enzymes responsible for the breakdown of serotonin and dopamine molecules. Therefore, these molecules remain in synaptic clefts longer and stimulate target neurons more effectively. On top of these effects, the extract of St. John’s Wort sensitizes the receptors of the main inhibitory neurotransmitter in the nervous system – GABA – which plays a crucial role in stress resilience and emotional stability. All in all, thanks to these mechanisms the combination of rhodiola and St. John’s Wort helps to improve the mood. Moreover, it boosts the ability to deal with stress, even in tough circumstances.

Improves attention: The extract from rhodiola contains compounds that inhibit the activity of monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) – enzymes that break down dopamine – a neurotransmitter that is responsible for the ability to focus and smoothly move the loci of attention. Therefore, it determines the span of working memory – a cognitive process that is essential for handling multiple tasks at the same time. St. John’s Wort, on the other hand, keeps the molecules of dopamine in synaptic clefts longer, and therefore affects their target receptors more effectively. Extract from this plant also contains compounds with similar properties to MAO inhibitors. Additionally, it upregulates the activity of glutamate – the main excitatory neurotransmitter in the central nervous system which underlies proper information acquisition and processing. The combination of these effects significantly improves the ability to concentrate, supports learning efficiency, and increases motivation. 

Boosts energy level: Dopamine and noradrenaline are two excitatory neurotransmitters involved in managing the level of energy and motivation. Biologically active compounds found in extracts of rhodiola and St. John’s Wort prevent the molecules of these neurotransmitters from premature decomposition and therefore allow them to affect target receptors longer. This is why these herbs boost energy and enhance motivation. Additionally, Hypericum perforatum exhibits properties that optimize the functioning of mitochondria that produce energy which fuels neurons. Because of that, the efficiency of brain cells increases and so does intellectual performance.

RHODIOLA + ST. JOHN'S WORT formula specification


  • preparation in gelatin capsules
  • 2 capsules daily unless advised otherwise by a professional
ACTIVE (850 mg / 2 caps.)


  • gelatin capsules (white-red)


  • airtight PET bottle 120 ml with an inductive seal
  • desiccant packet Tyvek™ Microbag
  • netto weight: 31.5 g / 60 caps.
  • nutrition, neuroregulation, herbal medicine, clinical studies
  • ingredient admitted to trading in the EU and the US

RHODIOLA + ST. JOHN'S WORT formula usage

  • 2
  • 1 – 2
  • with food
  • in the morning / during the day
  • 6 weeks of using – 2 weeks of break

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.