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PRL-8-53 + ALPHA-GPC is a synergistic preparation for those who need to work at full capacity. It is able to improve energy and motivation while supporting attention. It also has a positive influence on memory, especially working memory. Besides that, this formula supports information acquisition and learning abilities. Thanks to energizing properties, it will be a decent remedy for procrastination.


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Formula PRL-8-53 + ALPHA-GPC

PRL-8-53 is a nootropic compound that was synthesized for the first time in the 1970s in the United States. It has a great potential to support motivation which makes it an excellent response to issues such as procrastination or complete lack of energy. By influencing dopamine activity, it significantly improves the willingness to act and self-perceived energy level. To maximize its nootropic potential, we decided to combine it with one of the best available sources of choline – alpha-GPC. This compound also stimulates dopamine activity in the brain as it takes part in the regulation of dopamine metabolic pathways. Because of that, it enhances the effects of PRL-8-53. Furthermore, both components of this synergistic combination help to improve cognitive abilities. In particular, they support efficiency of concentration and memory. ALPHA-GPC is a highly available source of choline which is able to significantly increase the level of acetylcholine – one of the most important neurotransmitters that makes the brain cells work more effectively, and makes it easier to learn new things. 

Formula PRL-8-53 + ALPHA-GPC is recommended for people who require a lot from themselves and want to take full advantage of their mental capability in a short time. Our formula can be effectively used as a solution for procrastination but it will also work well as a support during the periods of intense work or study. It is worth noting that the best results may be achieved when using this preparation on an ad hoc basis.

Ingredients of PRL-8-53 NooSynergy™:

PRL-8-53 | Pirotropil™
  • 6 mg / 2 caps.
PRL-8-53 is a synthetic nootropic compound invented in the second half of the 20th century. It is especially effective in terms of neurotransmitter activity regulation. It stimulates dopamine receptors increasing the activity of this neurotransmitter in the nervous system. In effect, the level of motivation goes up. PRL-8-53 can also stimulate acetylcholine receptors, which brings better memory and attention. Since this compound facilitates blood flow in the brain while increasing the intake of oxygen and glucose, it has a positive effect on the neuronal activity.
Alpha-GPC | Choline alphoscerate
  • 600 mg / 2 caps.
ALPHA-GPC is a phospholipid that naturally occurs in the nervous system. It is a great source of choline with high bioavailability. It is easily absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Alpha-GPC supports proper functioning of the central nervous system by providing a precursor to the production of acetylcholine but also by regulating the activity of other neurotransmitters, including serotonin, dopamine and GABA. Thanks to that, it helps to boost one’s mood. In addition, Alpha-GPC improves blood flow in the blood vessels of the central nervous system, which brings better oxygenation and more efficient functioning of neurons. Muscles are also affected by this phospholipid as it improves coordination of the whole body and stimulates the growth hormone secretion. That, in turn, supports good physical performance and regeneration, especially after an intensive workout.
Phosphatidylcholine | Helianthus annuus
  • 194 mg / 2 caps.
Phosphatidylcholine is an organic compound from the group of phospholipids. It is a choline derivative made of choline and phosphoglyceric acid. It can be found in all bodily cells as an important ingredient of cell membranes. Phosphatidylcholine supports natural antioxidative compounds that occur in the brain and thus protects the nervous system from free oxygen radicals. Besides that, p-choline has an important role in the production of myelin sheaths that surround neurons and act as an insulator improving the speed of information processing. It is worth noting that it also influences the activity of main neurotransmitters, including acetylcholine. Hence, phosphatidylcholine is an effective support for cognitive functions and the ability to acquire new information as well as positive attitude. Since this compound participates in many metabolic processes and lowers cholesterol level, it has been found to support the condition of the liver.

PRL-8-53 + ALPHA-GPC formula benefits

Increases motivation: Dopamine is one of the most important stimulatory neurotransmitters. For some, it might be considered as “fuel for mind” because it mainly affects brain regions responsible for energy and motivation. When its activity decreases, fatigue and procrastination are more likely to occur. The results of scientific studies have shown that PRL-8-53 has a direct effect on dopaminergic receptors and stimulates them, imitating the effects of their natural ligands. Alpha-GPC is also involved in the regulation of dopamine metabolism. By increasing the activity of this neurotransmitter, the “reward system” in the brain is able to work more efficiently. This, in turn, may bring greater satisfaction with our own activities.

Improves attention: Dopamine is the most active in the prefrontal cortex – a brain region responsible, among other things, for attention and information analysis. These two elements are necessary to perform multiple tasks at the same time – this requires the ability to quickly transfer focus between different objects. This is the responsibility of  working memory where the information is only saved for a very short time. By increasing dopamine level, PRL-8-53 increases short-term memory capacity and supports the so-called multitasking. Alpha-GPC is no less important as it is one of the most efficient sources of choline – a compound that is essential for acetylcholine production. The combination of these two components effectively supports the ability to concentrate.

Supports learning process: PRL-8-53 is able to increase dopamine activity which may have a positive effect on attention. Proper acetylcholine level is equally important in terms of effective learning. If we were to think about dopamine as fuel, acetylcholine acts more like an accelerator. This is because it determines how fast the brain processes data and how well pieces of information are linked with each other. Choline alphoscerate is a source of raw material that can be used in the production of this neurotransmitter, and PRL-8-53 intensifies this process. Scientific research shows that Alpha-GPC improves blood flow in blood vessels supplying the central nervous system. Thanks to that, neurons can achieve more oxygen, glucose and other essential nutrients that help them to work better.

PRL-8-53 + ALPHA-GPC formula specification

  • preparation in gelatin capsules
  • 2 capsules daily unless advised otherwise by a professional
[800 mg / 2 caps.]
  • airtight PET bottle 100 ml or 150 ml
  • nutrition, neuroregulation, herbal medicine
  • ingredient admitted to trading in the EU and the US

PRL-8-53 + ALPHA-GPC usage

  • 2
  • 1 – 2
  • without food
  • in the morning / during the day
  • use occasionally – max. 3 – 4 times a week

PRL-8-53 + ALPHA-GPC formula stacking

To improve motivation:
To support attention:
To support learning:

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.