Oxiracetam | Oxitropil™

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Oxiracetam is a popular nootropic compound that belongs to the group of racetams. It effectively enhances cognitive abilities by increasing the activity of acetylcholine and dopamine in the brain. Thus, oxiracetam supports the process of information acquisition as well as information processing. It is also an interesting solution for those who want to improve their attention abilities.


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Oxiracetam | Oxitropil™

Properties: Oxiracetam is a synthetic compound with nootropic properties. Its beneficial influence on the nervous system stems mostly from its effects on the activity of key neurotransmitters: acetylcholine, dopamine, and glutamate. The key benefit of oxiracetam supplementation is its positive impact on two crucial cognitive abilities: learning and memory.  This effect is a direct result of improved acetylcholine secretion. Moreover, oxiracetam stimulates neuronal connectivity and thus, makes information transmission more efficient. Then, gathering knowledge becomes easier and faster. The mind registers more pieces of information while simultaneously maintaining clarity and avoiding overstimulation. The improved activity of acetylcholine supports the memory too, especially the aspect of information recollection. This effect is strengthened by the influence of glutamate on neuronal signaling. What is more, acetylcholine is also responsible for our ability to focus. When its activity is optimal, it becomes easier to maintain concentration on a given task. Thus, we avoid distractions and our productivity peaks.   

Additionally, oxiracetam supplementation brings about the upregulation of dopamine level. Since this neurotransmitter stimulates the so-called “reward system”, it is crucial for good mood and motivation – especially in combination with acetylcholine. In sum, oxiracetam is an excellent support to the intellectual capacities of the mind. It helps to get the best learning outcome, while simultaneously it takes care of our mental health.

Occurrence: Oxiracetam, just like other racetams, does not occur in nature. Instead, it is synthesized in the laboratories.

Biochemistry: Oxiracetam (ISF 2522) is an organic chemical compound classified as a racetam. As all substances from this family, its molecule contains a 2-pyrrolidone ring, which is a derivative of gamma-aminobutyric acid (GABA). It is the equivalent of piracetam, which differs in the presence of a hydroxyl group on the fourth carbon atom in the pyrrolidine ring. This structural difference increases the bioactivity of oxiracetam. It is absorbed from the digestive tract well, and its bioavailability reaches up to 82%. Its blood plasma density peaks between 1 and 3 hours after administration. About 84% of the administered dose is expelled unchanged with urine. 

Oxiracetam easily crosses the blood-brain barrier. In the central nervous system it increases the activity of the main excitatory neurotransmitter – glutamate – through an interaction with positive allosteric modulators of AMPA receptors. Moreover, it upregulates the level of acetylcholine – an excitatory neurotransmitter especially relevant for the hippocampus, a key structure responsible for memory processing.

Fun fact: Up to this day scientists discovered 17 compounds that belong to the group of racetams. Besides oxiracetam the group includes popular nootropic substances such as: aniracetam, nefiracetam or coluracetam. The other interesting examples are brivaracetam and omberacetam (commonly known as noopept).

How does Oxiracetam | Oxitropil™ work?

Improves learning abilities: The long-term synaptic potentiation (LTP, long-term potentiation) is fundamental to the process of information acquisition. Its main mechanism relies on repetitive stimulation of target connections. This makes them stronger, which, in turn, optimizes the signal transmission. The results of multiple studies confirmed that oxiracetam activates LTP, perhaps via stimulation of certain neuronal signals. Therefore, it makes learning new facts and skills easier.

Supports memory and concentration: Acetylcholine is a neurotransmitter responsible for proper memory functioning. Additionally, it helps to keep the locus of attention on a particular task. Oxiracetam stimulates activity of acetylcholine in the central nervous system, especially in the hippocampus – a structure crucial for memory processes. It is proven that this supplement increases the neuronal reuptake of choline (a substrate needed to produce this neurotransmitter) by 30%. In this way, it increases the activity of acetylcholine and in turn – benefits the memory capacities. Scientists have noted that the oxiracetam’s influence on memory is stronger when it is supplemented regularly relative to a single dose. Importantly, its effects last longer than the period of supplementation – they were prominent even four months after the last administration.

Improves general mood: Dopamine is a neurotransmitter crucial for mental comfort. It is secreted mainly during the activation of the brain’s reward system. Scientific evidence shows that oxiracetam influences the secretion of dopamine and prevents its lowering in adversarial conditions. What is more, its effects on other excitatory neurotransmitters – acetylcholine and glutamate – are also relevant. When their combined activity is optimal, it becomes easier for us to maintain a positive mood and stay highly motivated.

Provides energy to learn:  Multiple research studies claim that oxiracetam has psychostimulatory properties. Foremostly, it increases the activity of glutamate, the main excitatory neurotransmitter. It works as a positive allosteric modulator for its receptors. In simpler terms, it makes the connectivity between receptors and molecules of this neurotransmitter smoother. This leads to a noticeable surge of energy and an improvement of cognitive abilities. What is more, oxiracetam improves the activity of acetylcholine. As a result, the efficacy of information processing by the brain increases. Thus, the mind can reach its optimal performance.

Oxiracetam | Oxitropil™ product specification


  • powdered raw ingredient
  • oxiracetam >99%;  pharmaceutical quality
  • PET measuring tool 0.5 ml ~ 400 mg
  • airtight ALU-PET bag
  • nutrition, neuroregulation, herbal medicine
  • ingredient admitted to trading in the EU and the US

How to use Oxiracetam | Oxitropil™?


  • 400 – 800 mg
  • 1 – 2
  • without food
  • in the morning / during the day
  • 6 weeks of using – 2 weeks of break

How to stack Oxiracetam | Oxitropil™?

To facilitate information acquisition:
To improve memory and attention:
To improve general mood:
To increase energy level:

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.