OIL-BOX™ Cannabis Synergy

Protection and recovery of the nervous system: Scientific findings prove that cannabidiol and cannabigerol are beneficial to the nervous system. In the tests conducted with animal models of neurodegenerative disorders, these compounds were confirmed to alleviate inflammation within the brain. They reduce the secretion of pro-inflammatory cytokines from microglia cells and normalize the activity of immune cells. They also inhibit the expression of genes associated with the pathophysiology of some neurodegenerative diseases. Moreover, they reduce the effects of certain toxic substances on neurons, such as beta-amyloid, whose deposits are associated with the development of Alzheimer’s disease. CBD and CBG have also been proven to stimulate brain regeneration. This is because they enhance neurogenesis, the process of generating nerve cells. They influence synaptic plasticity, as they modulate the expression of genes related to the formation of connections between neurons. In this way, CBD and CBG protect the nervous system and help to improve cognitive abilities.

Supports stress resilience: People using preparations with CBD and CBG have repeatedly observed soothing effects of these compounds, including a decrease of nervous tension and improvement of mood, as well as increased efficiency of body recovery during sleep. The mechanism responsible for these effects is not yet well understood. However, scientists speculate that it might be related to the influence of these compounds on neurotransmitter activity in the central nervous system. CBD and CBG can affect GABA as well as opioid receptors. They can also influence the expression of genes involved in the release of dopamine, glutamate, GABA and serotonin. As a result, they reduce sensitivity to stress, and make it easier to calm down before bedtime, facilitating falling asleep. The participants of clinical trials confirmed that after taking CBD and CBG, they could feel significantly more relaxed, their mood improved, and their sleep was more efficient.

Helps to regulate the immune system: According to numerous studies, CBD and CBG are great in counteracting the excessive spread of inflammation. They have been proven to reduce the release of pro-inflammatory cytokines and inhibit the activation of Th lymphocytes as well as macrophages. Instead, they stimulate the anti-inflammatory effects of neutrophils. And since they influence the endocannabinoid system, they are able to alleviate pain associated with continuous inflammatory processes. There have been multiple tests conducted with animal models of inflammatory disorders. The results show that the use of CBD and CBG helps to reduce swelling, but may also slow down the development of these conditions. Similar results were obtained during a study involving people struggling with rheumatoid arthritis. After a few weeks of therapy, the patients reported that their symptoms improved. Besides that, CBD and CBG inhibit the growth of many microbial species, including antibiotic-resistant bacteria. They have also been proven to mitigate the proliferation of certain cancer cells and lead to their destruction. All these properties combined make CBD and CBG a valuable support for the body’s natural immunity.

Supports general health condition: CBD as well as CBG show a wide range of health-promoting properties that bring benefits for the entire body. These compounds act as powerful antioxidants, most likely even more effective in that regard than ascorbic acid (vitamin C) or tocopherol (vitamin E). They efficiently reduce the level of reactive oxygen species and protect cells from their harmful effects. In addition to that, they can be particularly beneficial for the circulatory system. CBD and CBG help to regulate blood pressure and prevent its excessive elevation – both at rest and during exercise or stressful situations. These cannabinoids are also able to reduce arterial stiffness and inhibit platelet aggregation, thus improving blood flow in the vessels. Their anti-inflammatory properties can be beneficial for people dealing with inflammatory bowel disease (IBD). Research with animal models indicates that CBD and CBG may lead to a reduced free radical production, alleviate inflammation and improve intestinal functioning. The researchers suggest that there should be human clinical trials conducted to confirm these findings. Moreover, CBD and CBG have a great influence on skin condition. They normalize sebum secretion, reduce sebaceous cell proliferation, and show anti-acne properties. These compounds can also be valuable in overcoming addiction. During research studies, the participants who used cannabinoids smoked 40% fewer cigarettes than usual and did not report increasing nicotine cravings.