NEURO-BOX™ Serotonin

(3 client reviews)

NEURO-BOX™ SEROTONIN is the most efficient solution for high serotonin deficits. Thanks to a special combination of amino acids, herbs and vitamins this formula makes it easier to regain inner balance and live life to the fullest. It will bring a refreshing, healthy sleep and support regeneration that occurs during night. It is also a great way to improve stress resilience and the general mood.


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NEURO-BOX™ Serotonin formula properties

NEURO-BOX™ SEROTONIN is the most comprehensive composition that will be particularly useful for high deficits of serotonin. When serotonin activity is deteriorated, we might have a terrible mood and feel exhausted all the time. Sometimes even a solid, long sleep does not regenerate our body at all. Serotonin depletion can be related to issues such as dependency, depression, reduced ability to experience pleasure, overthinking and constant worrying as well as anxiety, phobias and shyness.

  • NEURO-SERO™ Balance: Balancing Formula is based on high quality compounds that can be used as a foundation of the whole neuroregulation process. They include precursors and cofactors necessary for the proper synthesis of serotonin. They can also affect serotonin receptors, further improving the activity of this neurotransmitter. However, when those substances are not supplied regularly, serotonin activity might deteriorate. With our unique formula it is possible to support processes that will lead to an improvement of that activity.
  • NEURO-SERO™ Active: Activating Formula is a unique composition of herbal extracts that have been proven to support serotonin activity. They contain high amounts of biologically active compounds that stimulate natural processes that occur in the organism. This way, our formula intensifies the production of serotonin and sensitizes receptors of this neurotransmitter to make it more efficient. The Activating Formula helps to optimally use the elements provided with the Balancing Formula and thus supports the process of neuroregulation.

Ingredients of NEURO-SERO™ Balance (proprietary formula):

L-tryptophan is an amino acid that builds cell membranes and takes part in a synthesis of hormones and neurotransmitters. It is not produced in the human organism and that is why it has to be provided externally. L-tryptophan is a sole direct precursor of serotonin but indirectly it is also important in production of melatonin - the “stress hormone”. It provides a better mood and reduces stress symptoms. At the same time, tryptophan makes falling asleep easier and improves functioning of the digestive system.
Inositol | Myo-Inositol
Inositol is a compound that naturally occurs in the human body. It builds cellular structures. It also regulates signal transmission between neurons and affects the activity of neurotransmitters in the brain - particularly serotonin - as an activator of calcium channels. What is more, inositol influences GABA activity by interfering with its receptors. Because of that, this substance provides better mood, helps to deal with stress and is effective in the fight against addictions. It also has a key role in the process of neurogenesis as well as expression of genes that are associated with the proper functioning of the nervous system. And those are the things that keep the brain in good condition.
SAM-e | S-Adenosyl methionine
S-Adenosylmethionine (SAM-e) is a natural compound that acts as a nootropic and antioxidant. In terms of chemistry, it is a derivative of adenosine and methionine. This substance is key to many chemical reactions that occur in the human body. It is also quite important for the nervous system because it regulates neurotransmitters. SAM-e supplementation raises mental comfort because this compound stimulates receptors of serotonin - the so-called “happiness hormone” - but also dopamine that activates the reward system in the brain. SAM-e supports acetylcholine activity, and in effect, provides better memory and attention.
TMG | Trimethylglycine
Trimethylglycine is a methyl derivative of glycine that exhibits detoxifying and neuroprotective properties. TMG supports the conversion of homocysteine into methionine. This, in turn, is an important stage in the process of glutathione production. Thus, TMG takes part in the production of the strongest natural antioxidant. It also stimulates growth hormone secretion, increasing physical capabilities of the body, especially during a demanding physical activity.
Calcium | BioCalcium™
  • 160 mg (as calcium glycinate) | 20% RDA
Calcium is one of the micronutrients that are crucial for the proper functioning of the human organism. It regulates the permeability of cell membranes, controls acid-base balance and also facilitates signal transmission between neurons. Besides that, iron supports the functioning of the heart, blood flow and muscle contraction. Keep in mind that this element is crucial for the bones as it makes them more durable.
Vitamin B3 | Niacine
  • 16 mg (as nicotinic acid) | 100% RDA
Vitamin B3 supports the production of energy in the cells and regulates neurotransmitter activity. It also stimulates the synthesis of acetylcholine, serotonin and GABA. From the chemical perspective, it is a composition of two compounds: nicotinic acid and its derivative - nicotinamide. Vitamin B3 can be found in numerous food products, such as meat, fish, seafood, vegetables (pepper, potatoes and asparagus), whole grain wheat, peanuts as well as legumes.
Vitamin B6 | Pyridoxine
  • 4.2 mg (as pyridoxine hydrochloride) | 300% RDA
Vitamin B6 is a key compound that supports proper functioning of the central nervous system, particularly in terms of maintaining a positive attitude. It is a cofactor in the production of neurotransmitters, including GABA, dopamine and serotonin. Besides that, vitamin B6 is important for metabolic processes that occur in neurons and protects those cells from premature degeneration. It can be found in food products, such as soy, yeast, chickpeas, starchy vegetables, bananas, fish and meat.
Vitamin B9 | Folic acid
  • 0.4 mg (as folic acid) | 200% RDA
Vitamin B9 is crucial for the proper functioning of the nervous system as it participates in the production of important neurotransmitters, including serotonin and dopamine. It also facilitates detoxification processes that occur in the body by protecting the liver and kidneys. It has been proven that oxidative properties of vitamin B9 make this compound a valuable support for premature aging prevention. It protects the DNA from mutations and thus helps to maintain vitality.

Ingredients of NEURO-SERO™ Active (proprietary formula):

Curcumin | Curcuma longa
Turmeric, also known as curcuma, is a flowering plant that in Ayurveda is considered to be one of the most important herbs that act as a tonic and effectively support the organism. It comes from India, however, ancient Europeans already knew turmeric and widely used it. Although it is a very tasty spacy, we should probably focus even more on its health-promoting properties. The main herbal resource of curcuma is the rhizome that contains curcumine - a main active compound. Curcumine has strong anti-inflammatory and antioxidant properties which support the immune system. It also positively affects the nervous system as it has neuroprotective properties. What is more, curcumine stimulates the activity of BDNF - a protein that stimulates new nerve cell production and helps to create connections between the neurons. This mechanism is crucial for the condition of the nervous system and improves learning abilities of the brain. Moreover, curcumine can also improve mood. This compound stops the mechanism that breaks down neurotransmitters but also helps to reduce cortisol - the “stress hormone”. Because of that it is much easier to keep emotional balance.
Garcinia cambogia
In the Ayurveda, tamarind extract has been used in order to support the proper functioning of the digestive system. In the 1960s, scientists have proven that tamarind can be used by the people who want to lose some weight. Garcinia helps to regulate metabolism of fats and increases the production of glycogen which is responsible for the feeling of satiety. Tamarind also lowers cholesterol levels in blood, particularly the “bad fraction” - LDL - that in excess may lead to atherosclerosis. The extract of G. cambogia helps to boost lowered mood since it stimulates the activity of serotonin - a “happiness hormone”. The most important active compounds of tamarind are hydroxycitric acid (HCA) and a polyphenol called garcinol.
Gou Teng | Uncaria rhynchophylla
Gou-teng is an herb with neuroprotective properties that has been used in traditional medicine of the Far East. Contemporary studies prove that it is a great support for the central nervous system. It stimulates mitochondria that provide neurons with the proper amount of energy. It also increases neurogenesis - the process of new nerve cells production. That way, Gou-teng supports regenerative capabilities of the nervous system. What is more, U. rhynchophylla stimulates the activity of neurotransmitters - GABA and serotonin - which significantly improves mood, reduces stress and helps to sleep better.
Jujube | Ziziphus Jujuba
Jujube is a plant that has been used in natural medicine of Asia as a relaxing, analgesic and strengthening remedy. Contemporary research studies prove that natural compounds contained in the fruits of Jujube have antidepressant and anxiolytic properties and can even be used in order to treat insomnia. They support the activity of GABA - the neurotransmitter that helps to deal with stress and “cool down” the whole organism. What is more, this plant has a beneficial effect on the digestive system as well as the whole condition of the body, by supporting atherosclerosis prevention. Jujube is also effective when combined with ginger because it prevents exhaustion of the organism that might be caused by warming properties of ginger.
Polygala tenuifolia
Polygala tenuifolia is an herb that occurs in the widespread areas of Asia. It can be found mostly in China, Mongolia and Russia. It is very popular in Traditional Chinese Medicine, where it is known as Yuan Zhi. However, natural Japanese medicine as well as Ayurveda also use this plant. Polygala supports cognitive functions and improves intellectual performance. The active compounds found in this herb increase the activity of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). This way, polygala extract affects the processes of neurogenesis and neuroplasticity that lead to creation of new nerve cells and connections between them. Those processes are especially important in terms of learning abilities and memory. What is more, polygala stimulates the activity of choline acetyltransferase (ChAT) - an enzyme that transforms choline into acetylcholine - a neurotransmitter responsible mainly for proper information exchange between neurons.
Phosphatidylserine | AlphaSerine™
Phosphatidylserine is a compound that naturally occurs in the human organism. It is one of the main phospholipids that build all of the cell membranes. The highest concentration of this substance can be found in the brain, particularly in the cortex and hippocampus, and that is why phosphatidylserine has great influence on the nervous system. Primarily, it improves efficiency of signal transmission between cells and regulates secretion of neurotransmitters as well as hormones. It affects the activity of acetylcholine, dopamine and noradrenaline - the substances that provide better mood, cognitive functions and motivation. Moreover, phosphatidylserine helps to reduce stress symptoms because it inhibits cortisol - the so-called “stress hormone”. In addition, this compound increases the intensity of alpha brain waves, which are associated with relaxation and mood stability.
Saffron | Crocus sativus
Saffron is a plant known for its good influence on mood and libido. It has been used by the human kind for about 3000 years but it became the most popular in the Mediterranean Basin. The biologically active compounds of crocus, including safranal, crocin and crocetin, show antidepressant, nootropic and libido-stimulating properties. Saffron is also an antioxidant that supports the functioning of the cardiovascular system, lowers cholesterol level in blood and facilitates weight loss.
Piperine | Piper nigrum
Piperine is an active compound that occurs in black pepper - one of the most popular spices used worldwide. It is the piperine that gives pepper its distinctive strong, spicy aroma and taste. This compound can be effectively used to support the nervous system as it significantly increases bioavailability of many other herbal ingredients that do not absorb very well on their own, e.g. curcumine that absorbs 20 times better when mixed with piperine. Besides that, piperine exhibits antioxidant properties which means that it helps to protect cellular structures, including DNA, from harmful effects of free oxygen radicals. Moreover, it might be a good support in weight reduction because it helps to regulate metabolism in fatty cells and stimulates lipid breakdown. In addition to that, piperine shows potential as a nootropic ingredient that supports the nervous system. It inhibits the activity of acetylcholinesterase that breaks down acetylcholine. Hence, the density of this neurotransmitter in synapses is higher. On top of that, piperine increases the level of the brain-derived neurotrophic factor in the hippocampus. In effect, long-term memory and the ability to acquire information is improved.

NEURO-BOX™ Serotonin formula benefits

Supports mental comfort:

  • Balance: Serotonin is probably the most renowned neurotransmitter that has an important role in terms of well-being and general mood. After all, it is sometimes referred to as a “happiness hormone”. Its proper activity is necessary to maintain a good mood and emotional balance. The Balancing Formula includes a serotonin precursor as well as ingredients that can act as cofactors in serotonin production. There are also compounds that modulate the activity of this neurotransmitter, e.g. by inhibiting its reuptake. Thanks to that, in the synapses there are more molecules that can affect specific neurons. The ingredients of the Balancing Formula are also cofactors in the synthesis of another important neurotransmitter – dopamine – inhibiting its reuptake and increasing the sensitivity of its receptors. All these effects combined make this composition an efficient support for a good mood.
  • Active: The ingredients contained in the Activating Formula also stimulate serotonin activity. They intensify the release of this neurotransmitter in the synapses, so it can stay active for a longer time. They can also reduce the activity of proteins that break serotonin down into other compounds and participate in its reuptake. Simultaneously, they stimulate the production of serotonin receptors, thus enhancing serotonin activity within the nervous system. Those natural ingredients are also able to affect dopamine by reducing removal of its molecules from the synapses and increasing sensitivity of dopamine receptors. Thanks to these mechanisms, the Activating Formula can bring improvement in mental well-being.

Helps to control body mass:

  • Balance: Serotonin has an important role in terms of emotional balance and a positive attitude but it’s not the only purpose of this neurotransmitter. It also affects the functioning of the hypothalamus where it helps to control appetite. The ingredients of the Balancing Formula increase serotonin activity in the brain which might be quite important for those who would like to eat a little less. And since this neurotransmitter induces mental well-being and reduces the intensity of stress, it can possibly help to stay away from snacks that sometimes can be eaten just to improve mood and bring momentary satisfaction. The special, herbal ingredients found in this Formula have been proven to normalize glucose level in blood and prevent its sudden changes. This is particularly important because unstable glucose activity might be one of the factors that lead to binge eating. And since the Balancing Formula helps to stimulate serotonin release, it actually might be a decent support for a balanced, healthy diet.
  • Active: The ingredients of the Activating Formula also raise the level of serotonin in the brain and normalize glucose concentration in blood, so they are able to influence appetite. However, that’s not all. Those ingredients help to get rid of energy resources stored in the form of fat tissue. They stimulate metabolism, especially in adipocytes that are the main fat cells. Besides that, they might be able to induce fat burning within muscles. Importantly, they have been found to improve physical endurance, so they might come in handy during workout which is also an important and recommended type of activity during weight loss. And since they facilitate absorption of nutrients from the digestive tract, even smaller portions of food might bring decent amounts of essential micro- and macroelements. All of these factors make the Activating Formula a great combination with the Balancing Formula in regards to weight control and having healthy dietary habits.

Helps to improve sleep quality:

  • Balance: Serotonin is especially important in terms of a positive attitude and inner comfort. However, it also acts as a direct precursor of another crucial neurotransmitter – melatonin – that regulates sleeping patterns and makes it easier to fall asleep. When the day is inevitably going towards a sunset and the light slowly fades, melatonin levels in the brain significantly rise. This is a signal for the body to prepare for a night’s rest. In that regard, it’s worth mentioning GABA – a neurotransmitter that helps to relax and calm down. The ingredients of the Balancing Formula have been proven to influence all those aspects of neuronal activity. All in all, they might be effective in the fight against insomnia, bringing relaxation and peace of mind before bedtime.
  • Active: The ingredients of the Activating Formula are able to improve the activity of serotonin and GABA but they have also been found to influence the adrenergic system. Adenosine is a neurotransmitter that has a vital role in a healthy and regular sleep because its level is particularly low in the morning right after we wake up and gradually gets higher during the day to reach peak in the evening, causing sleepiness and reducing neuronal activity. GABA and serotonin are a great support for this compound as they help to relax and reduce nervousness. Research results indicate that natural extracts contained in the Activating Formula might facilitate falling asleep but also make sleep longer and more stable, regulating patterns of REM and NREM phases. The first one is typical for memory consolidation and recovery of the mind while the second induces the most efficient recovery of the body. At the end of the day, this composition is a great choice for any person who wants to sleep comfortably and more regularly.

Improves stress resilience:

  • Balance: The proper activity of serotonin is important for psychological comfort. However, maintaining emotional balance all the time is very hard and perhaps even impossible. Yet, it might be easier to reduce stress and anxiety thanks to GABA that acts as an inhibiting neurotransmitter and blocks nerve impulses, counteracting agitation. The Balancing Formula of this NEURO-BOX™ includes cofactors that are necessary in GABA production as well as compounds that affect the receptors of this neurotransmitter and directly activate it or facilitate binding to natural ligands. The measurable effect of higher GABA activity is a lowered level of cortisol – a hormone that brings most of the unfavorable stress symptoms. This special composition of high quality compounds might be a great support for stress resilience and mental well-being.
  • Active: In terms of stress reduction, the Activating Formula has the best effects in improving the activity of serotonin and GABA. Those ingredients allow serotonin molecules to stay in the synapses for a longer time and in higher amounts, so they can affect neurons with greater results. And regarding GABA, it is worth noting that this formula is able to increase concentration of a key enzyme that participates in the production of this neurotransmitter but also might improve sensitivity of its receptors, mimicking the activity of their natural ligand. In addition to that, it has been proven that some of those natural ingredients may even promote alpha brain waves. Brain waves are cycles of electrical activity in the nervous tissue that builds the brain. Its frequency can be measured to estimate the state of the brain and its current functioning. Alpha waves are related to a relaxation with high cognitive awareness. In effect, it is easier to focus and acquire new information with less stress and anxiety.

Supports memory and attention:

  • Balance: The ingredients of the Balancing Formula have a wide range of properties and even though they are particularly effective as a support for a positive mood and mental well-being, they might also be a great choice for improvement of cognitive functions. Dopamine is very important in that regard as it helps to focus on a particular task and influences the processes related to logical reasoning. GABA, on the other hand, stabilizes attention and reduces nervousness which actually might be very beneficial for intense intellectual performance. What’s important, the Balancing Formula helps to maintain balance between GABA and glutamate – a main excitatory neurotransmitter. Because of that, the brain is less vulnerable to negative effects of excessive amounts of glutamate and thus can work more efficiently. The ingredients of this composition are beneficial for the brain yet for another reason. They intensify neurogenesis and neuroplasticity – two important aspects of neuronal activity that help to stimulate production of new nerve cells and participate in formation of new connections between them. Simultaneously, they support development of myelin sheaths that surround axons, protecting them and facilitating signal transmission between neurons.
  • Active: Herbal extracts contained in the Activating Formula also have a positive influence on memory and attention. As studies suggest, they might be able to stimulate production of BDNF and NGF – the proteins that promote neurogenesis and neuroplasticity. They also stimulate the process of dendritic branching which is an additional feature that supports efficient transmission of nerve impulses. And since those ingredients stimulate the activity of mitochondria, they can provide the cells with more energy that is necessary for them to function properly. Besides that, they protect the cells from a negative influence of different compounds, including reactive oxygen species and beta-amyloid (that is a major risk factor of Alzheimer’s disease). This herbal composition affects neurotransmitter balance as well. It may increase the activity of dopamine and GABA, stabilizing focus. What is more, it can also stimulate an enzyme that takes part in acetylcholine production and reduce the activity of a protein that breaks down molecules of this neurotransmitter. Acetylcholine is crucial for cognitive performance because it can facilitate information processing in the brain and support learning abilities. With this wide range of positive effects the Activating Formula will certainly make the brain’s functioning more efficient.

NEURO-BOX™ Serotonin formula specification

Formula NEURO-SERO™ Active:

  • preparation in gelatin capsules
  • 2 capsules daily or as advised by a healthcare professional
[1200 mg / 2 caps.]
  • airtight PET bottle 150 ml
  • nutrition, neuroregulation
  • preparation admitted to trading in the EU and the US

Formula NEURO-SERO™ Balance:

  • bulk powder mix
  • 1 portion daily (5 ml scoop) or as advised by a healthcare professional
[3330 mg / 1 portion]
  • airtight ALU-PET bag
  • nutrition, neuroregulation
  • preparation admitted to trading in the EU and the US

NEURO-BOX™ Serotonin formula usage

Activating Formula NEURO-SERO™ Active:

  • 2 capsules
  • 1 – 2
  • with food
  • in the morning / during the day
  • 6 weeks of using – 2 weeks of break

Balancing Formula NEURO-SERO™ Balance:

  • 3330 mg
  • 1 – 2
  • without food
  • in the morning / during the day
  • 6 weeks of using – 2 weeks of break

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.