Reduces stress: Melissa officinalis and Polygala tenuifolia help to achieve a state of relaxation by inhibiting unnecessary nerve impulses. Both ingredients of this synergistic recipe affect the GABA-ergic system. Let’s recall that gamma-aminobutyric acid (GABA) is one of the major brain chemicals whose receptors can be found in nearly all neurons. It is particularly important in the context of coping with stress, as its activity results in the alleviation of physiological responses to nervousness. Through research, it has been proven that biologically active substances contained in Polygala tenuifolia stimulate the production of GABA-A receptors and affect them similarly to their natural ligands. That way, the extract of this plant contributes to an increased activity of GABA, and thus helps to reduce nervous tension and facilitates emotional balance. Melissa supports the anxiolytic properties of Polygala, albeit due to different mechanisms. It has been shown that active compounds found in this herb are able to inhibit GABA aminotransferase – an enzyme that breaks down GABA. As a result, this neurotransmitter can affect the nervous system longer and more effectively.

Supports deep sleeping: The quality of sleep largely depends on the emotional state and agitation of the nervous system. Stress is one of the factors that can significantly disrupt natural sleeping patterns and sometimes even lead to insomnia. The ingredients of the MELISSA + POLYGALA formula mitigate intensity of stress reactions and have a calming effect on the entire nervous system, thus making it easier to fall asleep. The results of scientific research prove that active substances contained in lemon balm promote the NREM sleep phase, during which the body’s regeneration is particularly efficient. During clinical tests people struggling with insomnia have experienced roughly 85% improvement of sleep quality after using the extract of this herb. It should also be mentioned that Yuan Zhi contains biologically active compounds capable of stimulating adenosine – a neurotransmitter that plays an important role in regulating sleep-wake cycles. When the concentration of this neurotransmitter in the synaptic cleft gets higher, the feeling of sleepiness is induced and the organism is able to prepare for a good night’s rest. Since both ingredients influence key inhibitory neurotransmitters, they help to enjoy a balanced circadian rhythm.

Supports the nervous system: For centuries, Melissa officinalis and Polygala tenuifolia have been used by practitioners of natural medicine in order to improve intellectual performance. This is because besides relaxing effects this composition can also be quite efficient in regard to supporting cognitive functions. Studies suggest that active substances found in the leaves of Yuan Zhi intensify secretion of nerve growth factor (NGF) as well as brain-derived neurotrophic factor (BDNF). The presence of these compounds is necessary for neurogenesis and neuroplasticity to occur. In the course of neurogenesis more nerve cells are produced – mostly in the hippocampus, which is a brain structure responsible for memory and spatial orientation. Neuroplasticity, in turn, is defined as the brain’s ability to form new connections between neurons. These mechanisms are crucial for learning abilities and allow the brain tissue to remodel if necessary. The active compounds of lemon balm also stimulate neurogenesis and, in addition to that, influence the activity of acetylcholine – a key brain chemical that helps to maintain a proper level of attention and facilitates information processing.