MELISSA + POLYGALA is a synergistic formula with high quality, natural ingredients that support stress resilience and facilitate healthy sleeping. By stimulating GABA activity, this recipe helps to reduce the intensity of emotional reactions. It also promotes neurogenesis and brings positive effects to the condition of the nervous system as well as efficiency of cognitive functions.

15,99

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MELISSA + POLYGALA formula properties

Lemon balm (Melissa officinalis) is a plant that most likely does not need a lengthy introduction. An infusion based on this herb is considered by many as an effective way to calm a restless or anxious mind. However, it is worth remembering that Melissa, so popular for its deep, slightly citrus aroma, can actually bring numerous benefits for the overall condition of the organism. And it is no different for the second component of this composition – Polygala tenuifolia (also known as Yuan Zhi). This herb is particularly valued in Traditional Chinese Medicine. Masters of this ancient craft believe that Polygala root helps to maintain balance of qi life energy – especially within kidneys and the heart. That way, it is supposed to provide longevity and inner stability. Regardless of whether one recognizes this way of perceiving reality or not, the observations of ancient herbalists are being confirmed by modern scientific research.

The results of studies show that both Melissa and Polygala effectively help to calm nervous tension, making it easier to relax. The main mechanism by which the active compounds of these plants can affect the nervous system is stimulation of the activity of GABA – the main inhibitory neurotransmitter that helps to reduce the intensity of stress reactions and mitigates anxiety. This is also quite important in regard to the quality of sleep, which, after all, is a huge part of our lives. It is during sleep that memory consolidation and many other regenerative processes occur. It is, in fact, crucial to the good condition of the entire body – it enables recovery of muscle tissue, contributes to lower blood pressure, strengthens immunity and regulates biochemical processes within bodily cells. At times, due to stronger nervous excitation and stress we may keep tossing and turning in bed so it’s nearly impossible to fall asleep. Then this natural, balanced rhythm can be seriously disrupted. Therefore, it is worthwhile to take care of mental comfort particularly in the evening, when our body is being prepared for nighttime rest. Hence, in this synergistic combination, lemon balm and Yuan Zhi will help to reduce nervous tension, improving sleep quality.

Let’s also mention that both extracts have a beneficial influence on intellectual performance. Research indicates that ingredients of MELISSA + POLYGALA stimulate neurogenesis and neuroplasticity which are key processes for learning abilities. Thanks to them, new neurons can get produced and new connections between the cells are able to form efficiently. Moreover, those two herbs regulate the activity of acetylcholine – a brain chemical that has an important role in cognitive functions and efficacy of information processing. They can support not only mental comfort but also brain functioning.

MELISSA + POLYGALA is a synergistic combination of two excellent plants that induce a calming effect while supporting healthy and refreshing sleeping. We recommend it especially for people who want to take care of inner balance as well as enhance stress resilience. Since both these herbs exhibit nootropic properties, they will also come in handy to support the condition of the nervous system and cognitive functions.

Ingredients of Melissa BioSynergy™:

Lemon balm | Melissa officinalis
  • extract 10% rosmarinic acid (500 mg / 2 caps.)
Lemon balm is a plant widely known all over the world for its ability to reduce anxiety. The natural compounds found in this herb are ursolic acid and rosmarinic acid. Those substances catalyze the reaction of conversion of L-glutamate to GABA. The other active compounds can modulate the activity of GABA receptors. That is why lemon balm extract helps to reduce tension and other symptoms of stress. Melissa officinalis also helps to fall asleep faster if taken in the evening while providing better regeneration during the sleep - both mental and physical.
Yuan Zhi | Polygala tenuifolia
  • extract 20:1 (300 mg / 2 caps.)
Polygala tenuifolia is an herb that occurs in the widespread areas of Asia. It can be found mostly in China, Mongolia and Russia. It is very popular in Traditional Chinese Medicine, where it is known as Yuan Zhi. However, natural Japanese medicine as well as Ayurveda also use this plant. Polygala supports cognitive functions and improves intellectual performance. The active compounds found in this herb increase the activity of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). This way, polygala extract affects the processes of neurogenesis and neuroplasticity that lead to creation of new nerve cells and connections between them. Those processes are especially important in terms of learning abilities and memory. What is more, polygala stimulates the activity of choline acetyltransferase (ChAT) - an enzyme that transforms choline into acetylcholine - a neurotransmitter responsible mainly for proper information exchange between neurons.

MELISSA + POLYGALA formula benefits

Reduces stress: Melissa officinalis and Polygala tenuifolia help to achieve a state of relaxation by inhibiting unnecessary nerve impulses. Both ingredients of this synergistic recipe affect the GABA-ergic system. Let’s recall that gamma-aminobutyric acid (GABA) is one of the major brain chemicals whose receptors can be found in nearly all neurons. It is particularly important in the context of coping with stress, as its activity results in the alleviation of physiological responses to nervousness. Through research, it has been proven that biologically active substances contained in Polygala tenuifolia stimulate the production of GABA-A receptors and affect them similarly to their natural ligands. That way, the extract of this plant contributes to an increased activity of GABA, and thus helps to reduce nervous tension and facilitates emotional balance. Melissa supports the anxiolytic properties of Polygala, albeit due to different mechanisms. It has been shown that active compounds found in this herb are able to inhibit GABA aminotransferase – an enzyme that breaks down GABA. As a result, this neurotransmitter can affect the nervous system longer and more effectively.

Supports deep sleeping: The quality of sleep largely depends on the emotional state and agitation of the nervous system. Stress is one of the factors that can significantly disrupt natural sleeping patterns and sometimes even lead to insomnia. The ingredients of the MELISSA + POLYGALA formula mitigate intensity of stress reactions and have a calming effect on the entire nervous system, thus making it easier to fall asleep. The results of scientific research prove that active substances contained in lemon balm promote the NREM sleep phase, during which the body’s regeneration is particularly efficient. During clinical tests people struggling with insomnia have experienced roughly 85% improvement of sleep quality after using the extract of this herb. It should also be mentioned that Yuan Zhi contains biologically active compounds capable of stimulating adenosine – a neurotransmitter that plays an important role in regulating sleep-wake cycles. When the concentration of this neurotransmitter in the synaptic cleft gets higher, the feeling of sleepiness is induced and the organism is able to prepare for a good night’s rest. Since both ingredients influence key inhibitory neurotransmitters, they help to enjoy a balanced circadian rhythm.

Supports the nervous system: For centuries, Melissa officinalis and Polygala tenuifolia have been used by practitioners of natural medicine in order to improve intellectual performance. This is because besides relaxing effects this composition can also be quite efficient in regard to supporting cognitive functions. Studies suggest that active substances found in the leaves of Yuan Zhi intensify secretion of nerve growth factor (NGF) as well as brain-derived neurotrophic factor (BDNF). The presence of these compounds is necessary for neurogenesis and neuroplasticity to occur. In the course of neurogenesis more nerve cells are produced – mostly in the hippocampus, which is a brain structure responsible for memory and spatial orientation. Neuroplasticity, in turn, is defined as the brain’s ability to form new connections between neurons. These mechanisms are crucial for learning abilities and allow the brain tissue to remodel if necessary. The active compounds of lemon balm also stimulate neurogenesis and, in addition to that, influence the activity of acetylcholine – a key brain chemical that helps to maintain a proper level of attention and facilitates information processing.

MELISSA + POLYGALA formula specification

 

TYPE OF PRODUCT:
  • preparation in gelatin capsules
RECOMMENDED DOSE:
  • 2 capsules daily unless advised otherwise by a professional
INGREDIENTS:
[800 mg / 2 caps.]
PACKAGING:
  • airtight PET bottle 120 ml
INTENDED USE:
  • nutrition, neuroregulation, natural medicine
LEGAL STATUS:
  • preparation admitted to trading in the EU and the US

MELISSA + POLYGALA formula usage

CAPSULES PER SERVING:
  • 2
SERVINGS PER DAY:
  • 1 – 2
BEST ABSORPTION:
  • with food
WHEN TO USE:
  • in the evening / before bedtime
OPTIMAL CYCLE DURATION:
  • 6 weeks of using – 2 weeks of break

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.