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Manganese is crucial for maintaining the nervous system and psychophysical balance. Moreover, this element strengthens bones, increasing their mineral density. At the same time, it supports the work of the immune system, as it stimulates the production of cells that fight infections. As manganese has anti-inflammatory and antioxidant effects, it helps to support the vitality of the entire body.

VITAMINS AND MINERALS

Manganese | Manganese gluconate

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Manganese | Manganese gluconate

Properties: Manganese participates in the production of many enzymes that regulate basic bodily functions. This element is a cofactor in the production of compounds responsible for the formation of bone tissue. It helps ensure adequate levels of osteocalcin – a protein that regulates bone mineralization – thereby promoting bone strength. Moreover, manganese is important for the balanced work of the immune system. As an immunomodulator, it stimulates the body’s immune response to infections, while helping to reduce inflammation when it is too intense. The results of studies show that this element can alleviate the symptoms of inflammation in the joints. It also shows the ability to stimulate the activity of natural killer (NK) cells, which fight abnormal cells in the body, as well as those infected with various pathogens. Equally important in this context is the fact that manganese supports natural antioxidant mechanisms. It is a component of enzymes that neutralize free radicals, so it contributes to lowering the level of oxidative stress. This, in turn, benefits the overall vitality and well-being of the body. Adequate levels of manganese are also important in terms of well-being. Deficiencies of this micronutrient are usually associated with deterioration of mood, which is why it is so important to take adequate amounts regularly.

Occurrence: The richest dietary sources of manganese include: oatmeal, nuts (hazelnuts, walnuts, peanuts, cashews), sunflower seeds, cocoa, brown rice, groats (buckwheat, barley), pumpkin seeds, dried apricots, white beans, bread (whole wheat and whole grain), broccoli or parsley root.

Biochemistry: Manganese (Mn) is a chemical element in the transition metal group. In its pure form, it is a hard but brittle solid with a silvery gray color and a pink sheen. It is essential for the functioning of all living organisms, as it is a component of many proteins, including enzymes. It also serves as a cofactor for numerous oxidoreductases, transferases, hydrolases, lyases, ilomerases and ligases. There are about 12 mg of manganese in the body of an adult. It is located mainly within the bones, as well as in the liver and kidneys. In the human brain, it is an element of metalloproteins, such as glutamine synthetase present in astrocytes.

Fun fact: Manganese compounds have been used since prehistoric times. In France, cave paintings dating back 30-24 thousand years have been found using pigments based on this element. In ancient times it became an ingredient in iron production and for coloring glass purple. On the territories of Europe such glass was made even in the 3rd century BCE.

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

How does Manganese | Manganese gluconate work?

Improving overall vitality: Manganese is a cofactor for many enzymes, including those involved in bone formation. Low levels of this element often accompany osteoporosis. A study in an animal model of the postmenopausal period (in which bone weakening is not uncommon) showed that taking a manganese supplement helped to raise osteocalcin levels and increase bone mineral density. Too little manganese in the diet may also be linked to the development of metabolic syndrome. Manganese is also crucial for fertility. Its proper levels ensure good motility of sperm. In women, insufficient amounts of it can lead to ovulation disorders and to an increase in premenstrual syndrome (PMS) symptoms.

Free radical removal: Manganese is a key component of one of the isoforms of superoxide dismutase, which occurs in the mitochondria. This enzyme is among the most important mechanisms the cells use to get rid of excess reactive oxygen species. It also protects cell structures from damage caused by carcinogens, chemical toxins or radiation. The results of a study involving young women prove that taking a supplement containing this element is able to reduce the level of oxidative stress in the body. Further work is underway to confirm the effectiveness of manganese in this field.

Regulation of the immune system: The antioxidant properties of manganese lead to the reduction of oxidative stress as well as inflammation. Studies involving people with inflammatory joint complaints have shown that taking a supplement based on this element helps to alleviate the intensity of symptoms. The results of studies with animal models show that manganese can stimulate the immune system response. In particular, it improves the activity of macrophages, which are the first line of defense against infections. It also intensifies the activity of NK cells, which play a key role in fighting viruses and abnormal cells in the body.

Supporting mental comfort and the nervous system: The results of a study in Japan involving more than 3,500 people showed that reduced levels of manganese in the body are associated with a higher risk of mood disorders. The exact role of this element is not known, but scientists speculate that it is involved in the regulation of glutamatergic and GABA-ergic neurotransmission. The balance between these two spheres, the first of which determines the level of arousal and the second of which has a calming effect, is crucial for the proper functioning of the entire nervous system, also in terms of emotional stability. No less important is the fact that manganese can reduce oxidative stress and inflammation within the central nervous system, as these factors have been linked to the occurrence of mood disorders.

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

Manganese | Manganese gluconate product specification

 

PRODUCT TYPE:
  • powdered preparation
STANDARDIZATION:
  • manganese gluconate (>99%)
MEASURING TOOL:
  • red micro-spoon containing 8 – 9 mg of manganese gluconate (depending on the batch, information on the label)
PACKAGING:
  • airtight ALU-PET foil bag
  • desiccant packet Tyvek™ Microbag
INTENDED USE:
  • scientific research, dietetics, natural medicine, neuroregulation, production of supplements and cosmetics,
LEGAL STATUS:
  • The raw material is approved for trading in the EU.
ATTACHMENTS:

 
Certificate of Analysis

The specification above contains a description and composition of all available variants of a given product or set. Depending on the batch of a given raw material or set, some information may differ slightly from the description on the label. The product photo is for illustrative purposes only.

Under European Union law, this product or some of its ingredients may be classified as not intended for consumption (so-called novel foods, nutraceuticals, nootropic compounds). Before purchasing, please familiarise yourself with the legal regulations regarding the legality of using this product or its ingredients in the country of destination.

How to use Manganese | Manganese gluconate?

 

OPTIMAL SERVING SIZE:
  • 17 mg (100% RWS*)
OPTIMAL SERVINGS AMOUNT:
  • 1 – 2 per day
OPTIMAL ABSORPTION:
  • with or without food
OPTIMAL USAGE:
  • any time the day
OPTIMAL CYCLE DURATION:
  • 6 weeks of using – 2 weeks of break

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

How to stack Manganese | Manganese gluconate?

The information provided above is intended solely to raise awareness of the scientific and historical facts regarding the properties, effects and uses of a given preparation. The product description does not constitute medical advice and should not be treated as a recommendation for its use. Always consult your doctor or specialist before using any dietary supplement, herbal preparation or nootropics. Dietary supplements should not be used as a substitute for a balanced diet and a healthy lifestyle, which are essential for maintaining good health. Dietary supplements, herbal preparations and nootropics should not be combined with any medications. The above-described preparation should not be used by pregnant and breastfeeding women or by persons under 18 years of age. The product photo is for illustrative purposes only.

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