L-lysine is one of the main amino acids that build proteins necessary for muscle tissue. This compound has a positive effect on the condition of the skin and bones but also improves wound healing. It takes part in the production of antibodies, supporting the immune system. Lysine affects the activity of GABA receptors and regulates the level of cortisol, enhancing stress resilience.
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L-lysine | PharmaLysine™
Properties: Lysine is a great addition to any amino acid mixture designed to support development and strength of muscles. This compound comprehensively enhances formation of muscle mass since it is one of the main proteins found in muscle tissue. Simultaneously, it acts as a precursor of L-carnitine – a substance that regulates metabolism in cells. L-carnitine facilitates the transport of fatty acids to the mitochondria that produce ATP – the main energy carrier found in every single cell of the body. Lysine is thus an important compound that affects muscle development but also has a vital role in production of energy that powers the muscles.
It is worth mentioning that this substance participates in the development of cartilages, tendons and bones. And since we’re talking about the connective tissue, let’s note the fact that this amino acid improves absorption of calcium – a microelement crucial for strong and healthy bones. Besides that, lysine reduces the amount of calcium that gets removed with urine. In effect, it helps to maintain a proper level of this essential element in the body. In this context, we should also talk about the role of lysine in the synthesis of collagen. Since it participates in that process and prevents the breakdown of collagen, the bones maintain their durability and the skin can be more flexible.
What is more, lysine supports the immune system and regeneration of the organism. This amino acid is used to create antibodies – special proteins that are an important element of a proper defense mechanism. In addition to that, lysine is necessary for efficient and quick wound healing. As we mentioned, since lysine stimulates collagen synthesis, it strengthens the structure of damaged tissues and speeds up their recovery.
Ultimately, it has been proven that lysine can influence the activity of major neurotransmitters. It can affect the receptors of GABA – the main inhibitory neurotransmitter that has a huge role in stress resilience and relaxation – both in physical and mental sense. Moreover, this amino acid acts as a partial antagonist of a serotonin receptor 5-HT4 that regulates physiological response to stress. At the same time, lysine helps to lower the level of cortisol that is widely known as a stress hormone since it gets released in situations that involve high nervous tension. That way, by interacting with different brain chemicals lysine indirectly supports relaxation and emotional balance.
Occurrence: Lysine belongs to the group of essential amino acids that cannot be produced within the organism, so they have to be provided with food. Some of the richest sources of lysine include: fish (herring, mackerel, cod, salmon or tuna), beef, poultry, dairy and legumes (e.g. soy, pea, beans, lentils and chickpea).
Biochemistry: Lysine is an organic compound from the group of alpha-amino acids. For the first time, it was isolated by a German chemist and biologist Ferdinand H.E. Drechsel in 1889. Chemical structure of L-lysine has been described at the beginning of the 20th century. It was established that this compound has two forms, so-called enantiomers, whose molecules are a mirror image of each other. So, they are very similar but there is a difference in configuration of specific atoms. Enantiomer L is one of the 20 basic amino acids that build proteins.
In the human organism, lysine has many important functions. It participates in the synthesis of proteins that are then used to build muscle tissue. This compound facilitates absorption of calcium and supports mineralization of bones as well as synthesis of collagen that is vital for a good condition of the skin. Besides that, lysine is necessary for the immune system. It also facilitates regulation of blood sugar level. By influencing the activity of key neurotransmitters, this amino acid affects stress resilience.
Fun fact: Lysine can be used to obtain ε-polylysine – a polymer that contains 20-30 L-lysine residues. Polylysine is commonly used in the food industry as a preservative because it exhibits great antimicrobial effects.
How does L-lysine | PharmaLysine™ work?
Supports muscles and overall endurance: Lysine is one of the most important essential amino acids. This compound can be found in proteins that build muscle tissue as well as tendons, joints and bones. It participates in the synthesis of the main hormones and regulates the key enzymatic reactions that occur in the body. Lysine is also a decent support for recovery processes. During intense physical effort, e.g. resistance training, the muscle fibers can get damaged due to microtears. By stimulating the synthesis of proteins, this amino acid helps to rebuild the fibers, so after recovery they become stronger. It is worth mentioning that lysine acts as a precursor of carnitine – a compound that regulates the transport of long-chain fatty acids to the mitochondria where those acids get broken down due to the process of beta-oxidation. Following numerous metabolic transformations, carnitine helps to produce adenosine triphosphate (ATP), the main energy carrier. All in all, we may conclude that lysine is a key amino acid that helps the muscles develop properly and provides them with energy required to function efficiently.
Supports general health: Research studies show that regular intake of L-lysine helps to regulate glucose level in blood. This amino acid is able to increase sensitivity to glucose in bodily cells. Besides that, it reduces glycation of proteins in blood plasma – the process during which glucose molecules attach to the proteins. Since this process is usually an indicator of skin aging, L-lysine might help to take care of the skin appearance. Moreover, there are studies proving that supplementation with lysine can facilitate normalization of blood pressure in people who are dealing with deficiencies of this substance. Importantly, it can have a positive effect on absorption of calcium from food and reduce the amount of calcium that gets removed from the body with urine. After all, proper intake of this essential element is crucial for mineral density and durability of the bones. Because of that, lysine can provide support in prevention of rheumatoid arthritis. There is another mechanism that positively affects the connective tissue – the stimulation of collagen synthesis. That is actually very important as collagen is one of the main compounds that build joint cartilages and improve elasticity of the bones as well as firmness of the skin.
Supports general health: Research studies show that regular intake of L-lysine helps to regulate glucose level in blood. This amino acid is able to increase sensitivity to glucose in bodily cells. Besides that, it reduces glycation of proteins in blood plasma – the process during which glucose molecules attach to the proteins. Since this process is usually an indicator of skin aging, L-lysine might help to take care of the skin appearance. Moreover, there are studies proving that supplementation with lysine can facilitate normalization of blood pressure in people who are dealing with deficiencies of this substance. Importantly, it can have a positive effect on absorption of calcium from food and reduce the amount of calcium that gets removed from the body with urine. After all, proper intake of this essential element is crucial for mineral density and durability of the bones. Because of that, lysine can provide support in prevention of rheumatoid arthritis. There is another mechanism that positively affects the connective tissue – the stimulation of collagen synthesis. That is actually very important as collagen is one of the main compounds that build joint cartilages and improve elasticity of the bones as well as firmness of the skin.
Supports the immune system: Several studies confirm that L-lysine can have a positive effect on immunity since it participates in the production of antibodies. Interestingly, it helps to fight infections with herpes virus. This is based on the fact that structurally, a molecule of lysine is very similar to arginine – an amino acid that is used by Herpes simplex to replicate. As lysine concentration gets higher, greater amounts of this substance are being used instead of arginine which reduces proliferation of HSV and may even help with recovery of skin defects that occur during infection. What is more, lysine has an important role in wound healing since it speeds up rebuilding of damaged tissues by stimulating production of collagen – a protein that gets accumulated in the place of injury during the phase of proliferation, when the damaged cells are intensively recovered. There are also studies indicating that lysine supports regeneration of blood vessels. All these properties make this amino acid essential part of wound healing and recovery processes in the body.
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