L-DOPA 99% | Mucuna pruriens

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L-DOPA is a natural amino acid obtained from the seeds of Mucuna pruriens (a.k.a. velvet bean). In the nervous system L-DOPA acts as a direct precursor of two important neurotransmitters: dopamine and noradrenaline. When supplemented, it helps to increase the level of motivation, prolongs the span of attention and promotes psychological wellness. Moreover, by supporting hormonal balance, it improves sexual performance.

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L-DOPA 99% | Mucuna pruriens

Properties: Intuitively, it is clear that a direct precursor of dopamine will be pretty efficient at increasing the level of this neurotransmitter, right? Well, L-DOPA is precisely such a precursor. In a nutshell, it is a natural amino acid that takes part in the secretion of dopamine and two other neurotransmitters: noradrenaline and adrenaline. What are the properties of L-DOPA? And why exactly is  it relevant in the context of neuroregulation?

Dopamine in its pure form is not absorbed very well by the digestive tract. In contrast, L-DOPA is highly bioavailable, which basically means that it easily crosses the brain-blood barrier, and thus efficiently influences the central nervous system. This influence is related to the increase of motivation level and productivity. That shouldn’t be a big surprise, given that dopamine is the key excitatory neurotransmitter responsible mainly for the levels of energy and motivation, both physical and mental. It benefits our sophisticated cognitive capacities while simultaneously supporting motor functions of the body. 

On top of that, dopamine plays an important role in maintaining our positive mood. This neurotransmitter is responsible for the sensation of pleasure and its secretion is related to the stability of emotional states. Since dopamine can help us to prevent the occurrence of depressive episodes or mood swings, it is important to keep its level optimal! This way, it should be easier to keep a positive attitude and stay productive. What is more, L-DOPA supports the production of hormones responsible for the ability to focus. It is quite important, considering the fact that dopamine is involved here too, as it helps to focus and switch the loci of attention with less effort. It is crucial in terms of multitasking: the ability to complete the task at hand and smoothly move to another one. Therefore, the supplementation of L-DOPA will be especially helpful whenever we enter a “high season” full of different challenges. 

Noteworthy, dopamine also influences the pituitary gland – a structure that secretes several hormones influencing some of the most important functions of the human body. L-DOPA helps to balance the endocrine system and supports the production of hormones such as prolactin, gonadotropin, and the growth hormone. Additionally, sportsmen may find it useful, because it upregulates the secretion of testosterone and thereby increases physical performance.

Occurrence: L-DOPA is a derivative of tyrosine and therefore naturally occurs in the human organism. This amino acid can be also found in the seeds of velvet bean (Mucuna pruriens), broad beans (Vicia faba), Indian tamarind (Tamarindus indica) or saber canavalia (Canavalia gladiata).

Industrially, L-DOPA is obtained from the seeds of the velvet bean. Firstly, this plant contains the highest amount of this precious amino acid. Secondly, L-DOPA derived from velvet bean is more resistant to high temperatures.

Biochemistry: L-DOPA is an organic chemical compound classified as an amino acid. It is a derivative of L-tyrosine and acts as a direct precursor of dopamine, but also, indirectly, helps to produce noradrenaline and adrenaline – neurotransmitters formed as a result of enzymatic changes in dopamine. In contrast to dopamine, however, L-DOPA easily crosses the brain-blood barrier. In the central nervous system, it is converted into dopamine in the presence of vitamin B6.

Fun fact: L-DOPA is the key compound in the formation of marine adhesive proteins such as mussel proteins. It is believed to be responsible for water resistance and the ability of these proteins to harden quickly. Note that L-DOPA was isolated for the first time from the broad bean seeds in 1936, in India. Just two decades later, a Swedish neuropharmacologist A. Carlsonn discovered how L-DOPA affects the nervous system.

How does L-DOPA 99% | Mucuna pruriens work?

Increases the level of motivation: The extract of Mucuna pruriens contains L-DOPA – a direct precursor of dopamine. It easily crosses the brain-blood barrier and thus provides the central nervous system with the raw material for the production of this neurotransmitter. Dopamine is mostly responsible for the level of motivation and the degree of satisfaction when our goals are attained. Thus, an increase of dopamine results in a noticeable energy boost. Indirectly, L-DOPA influences the secretion of other catecholamines such as adrenaline and noradrenaline. When these two function optimally, we feel ready to act and have enough resources to complete our tasks.

Improves and stabilizes mood: Dopamine is a neurotransmitter that stimulates the reward system – a part of the brain that induces the feeling of pleasure. Thus, its optimal level basically helps us to feel happy with our lives. L-DOPA contained in the velvet bean seeds increases the level of dopamine and thus – improves the mood. The same neurotransmitter is related to the motivation level and the strength of will. Thus, when its level is high, we can combat addictions with better results. In clinical trials it has been demonstrated that systematic supplementation of M. pruriens extract leads to a downregulation of the cortisol density in the central nervous system. This hormone is secreted whenever we are stressed, and its blood level is considered a prime stress level marker. Hence, the ability to normalize the activity of cortisol, in combination with the pro-dopamine effect of L-DOPA, is responsible for the mood-stabilizing effect.

Supports physical performance: The research results show that the supplementation of velvet bean extract supports physical training endurance. There are two main motives for this effect. Firstly, L-DOPA increases the level of testosterone which helps to develop muscle mass faster. Secondly, it promotes the secretion of the growth hormone. In the studies conducted on this matter, the density of GH was higher as quickly as one hour after an administration of a single dose. This hormone produced in the pituitary gland plays a role in the metabolism of carbohydrates and lipids. In the first place, it increases the release of glucose from the liver and intensifies the lipolysis process – the breakdown of adipose tissue. Simultaneously, it inhibits lipogenesis and therefore prevents the accumulation of new fat reserves.

Promotes concentration: Dopamine is responsible for the level of motivation and helps to direct our resources towards the goal. By providing the brain with its direct precursor it is easier to focus on our targets and achieve them. What is more, L-DOPA influences not only dopamine level, but also indirectly stimulates the production of other important catecholamines, such as adrenaline and noradrenaline. The optimal level of these neurotransmitters keeps our reaction time short, promotes concentration, and fine-tunes motor control. The supplementation of this amino acid can thus be helpful whenever we are faced with tasks that require focus, precision, and timely performance.

L-DOPA 99% | Mucuna pruriens product specification

 

TYPE OF PRODUCT:
  • powdered raw ingredient
STANDARDIZATION:
  • extract from the seeds of Mucuna pruriens (>99% L-DOPA)
MEASURING:
  • steel measuring tool 0.30 ml ~ 300 mg
PACKAGING:
  • airtight ALU-PET bag
INTENDED USE:
  • nutrition, neuroregulation, herbal medicine
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

How to use L-DOPA 99% | Mucuna pruriens?

 

RECOMMENDED SERVING:
  • 150 – 300 mg
SERVINGS PER DAY:
  • 1 – 2
BEST ABSORPTION:
  • without food
WHEN TO USE:
  • in the morning
OPTIMAL CYCLE DURATION:
  • 4 weeks of using – 2 weeks of break

How to stack L-DOPA 99% | Mucuna pruriens?

To increase motivation level:
To stabilize the mood:
To improve physical performance:
To support concentration:

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.