Reduces symptoms of stress: The extracts of Uncaria rhynchophylla and Piper methysticum have anti-anxiety properties and are able to reduce the intensity of emotional reactions. The results of scientific studies have shown that methisitine pepper upregulates the activity of GABA – the main inhibitory neurotransmitter that reduces excessive nerve impulses, especially in response to strong emotions and other stressors. Moreover, this plant contains biologically active compounds such as kavapirons that stimulate GABAergic receptors within hippocampus and amygdala – brain structures strongly involved in emotional processing. Gou Teng supports the anxiolytic effects of Kava Kava. This plant contains uncarialins that act as agonists of 5HT1A receptors, and thus increase the serotonergic signaling in the brain. As the proper activity of serotonin is crucial to deal with anxiety responses, Gou Teng also helps to relieve symptoms of stress and to maintain emotional balance.

Supports a good mood: Both Kava Kava and Gou Teng have been used in natural medicine in order to reduce mental tension and induce relaxation. Modern research confirms these ancient insights and proves that both plants might influence the neurotransmitters involved in our emotional states: serotonin (“the happiness hormone”) and dopamine (related to motivation and satisfaction). Active compounds found in both plants act as inhibitors of an enzyme called monoamine oxidase B that is responsible for the metabolism of dopamine and serotonin. By inhibiting the activity of this enzyme, Kava Kava and Gou Teng allow the particles of both these neurotransmitters to remain in synaptic clefts longer, thus stimulating target neurons with better results. Therefore, the result is the improvement of general mood and more satisfaction.

Supports the central nervous system: Results of many research studies indicate that both Kava Kava and Gou Teng support the proper functioning of the central nervous system and enhance cognitive capacity. The extract of Uncaria rhynchophylla contains biologically active compounds that stimulate the activity of mitochondria – the cellular powerhouses. What is more, it has been proven that this herb activates the process of neurogenesis that is responsible for the formation of new nerve cells. Additionally, it helps to increase the cholinergic signaling within the brain that underlies our ability to acquire and process information. Kava Kava, on the other hand, contains biologically active compounds that influence the hippocampus and basal ganglia – the structures mainly responsible for attention abilities and memory. In this way, it supports the nootropic properties of U. rhynchophylla. Noteworthy, the extract of Gou Teng also exhibits neuroprotective properties. This herb contains many compounds, e.g. hirsutin that counteracts inflammation caused by malfunctioning microglia cells. All in all, this herbal composition helps to maintain a good condition of neurons.