COMFORTIL™ ORIGINAL is a neuroregulatory preparation that can relieve stress and help to maintain well-being. It contains high quality herbal extracts that comprehensively support the activity of GABA and other neurotransmitters responsible for mental comfort. It also has a positive effect on the functioning of the nervous system, supporting information acquisition as well as neuroregeneration.

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COMFORTIL™ Original formula properties

COMFORTIL™ ORIGINAL has been developed especially for people who struggle with a lot of stress. The formula of this preparation is based on synergy between natural ingredients. We decided to include herbal extracts that for centuries have been successfully used by the experts in the field of natural medicine. These ingredients help restore psychophysical balance, and as a result, make it easier to achieve a state of relaxation. One of the main mechanisms making this formula so interesting is the stimulation of GABA activity. GABA is an inhibitory neurotransmitter that plays a special role in the context of stress resilience. It reduces the stimulation of the nervous system – which is particularly important in situations that trigger anxiety. Due to the calming effect, it naturally helps to prepare the body for sleep.

Thanks to research, it has been proven that the ingredients of our preparation not only increase the density of GABA receptors, but also stimulate the enzymes involved in the production of this neuromodulator. In addition, they inhibit the breakdown of its molecules, so GABA can affect the functioning of neurons for a longer time. The increase in GABA activity is associated with the reduction of cortisol, also known as the “stress hormone”. Long-term nervous tension contributes to many disorders of both somatic and mental nature, which is why supporting this inhibitory sphere of the nervous system is extremely important. It is also crucial to take care of the condition of the brain and the efficiency of cognitive functions. COMFORTIL™ ORIGINAL brings numerous advantages in this matter. The ingredients of this preparation stimulate the activity of acetylcholine – a neurotransmitter that facilitates the transmission of signals between nerve cells and supports information processing. They also stimulate neurogenesis and neuroplasticity – mechanisms that underlie learning and memory, as they enable formation of new cells and the connections between them.

The unique COMFORTIL™ ORIGINAL formula supports the body on many levels, increasing resistance to stress and bringing benefits for intellectual abilities. This preparation will be a great daily support for the condition and functioning of the nervous system. It can also contribute to the improvement and stabilization of mood.

Ingredients of COMFORTIL™ Original (proprietary formula):

Lemon balm | Melissa officinalis
Lemon balm is a plant widely known all over the world for its ability to reduce anxiety. The natural compounds found in this herb are ursolic acid and rosmarinic acid. Those substances catalyze the reaction of conversion of L-glutamate to GABA. The other active compounds can modulate the activity of GABA receptors. That is why lemon balm extract helps to reduce tension and other symptoms of stress. Melissa officinalis also helps to fall asleep faster if taken in the evening while providing better regeneration during the sleep - both mental and physical.
L-Theanine | PharmaTheanine™
L-theanine is a natural amino acid considered to be a part of nootropic and compounds that support and protect the nervous system. It can be found in the leaves of common tea (Camellia sinensis) - making up to 3% of dried leaf mass. One of the main properties of L-theanine is the ability to improve stress resilience. This compound inhibits cortisol while stimulating the activity of GABA - a key neurotransmitter that helps to mitigate stress symptoms. Moreover, L-theanine stimulates alpha brain waves that are related to the state known as a “relaxed attention”, typical for activities requiring a high focus, e.g. meditation. Thanks to that, L-theanine makes it easier to concentrate on the task at hand. It also has a beneficial effect on memory because it stimulates the process of neurogenesis during which new neural cells are produced. In dietary supplements L-theanine is often mixed with caffeine because in this composition stimulatory effects of caffeine are more subtle yet more durable with much less side effects such as agitation or anxiety.
Magnolia officinalis
Magnolia officinalis is an herb that has been used in natural medicine of the Far East for centuries. The main herbal resources are the bark and the buds. Magnolia is known primarily for its antidepressant and anxiolytic properties. It supports the activity of GABA bringing a sustainable increase of stress resilience. It also affects the activity of serotonin - the so-called “happiness hormone”. It provides a better mood and helps to fall asleep. What is more, magnolia can regulate the level of acetylcholine which is responsible for cognitive functions, including learning capacity and focus.
Brahmi | Bacopa monnieri
Brahmi is a major plant used in Ayurveda. Its name refers to a high place in the hierarchy of traditional Indian medicine herbs that Brahmi achieved. This plant effectively regulates neurotransmitter activity, particularly acetylcholine, serotonin and GABA. It is estimated that Brahmi can make acetylcholine level even two times higher! Because of that it supports cognitive functions of the brain, reduces anxiety and helps to relax. In addition, Brahmi has neuroprotective properties, which means that it protects the nervous system from harmful factors. It has been proven that this herb stimulates natural antioxidants and slows down the process of brain aging.

COMFORTIL™ Original formula benefits

Improves stress resilience: The reaction to a stressful stimulus includes the activation of an interactive system called the hypothalamic-pituitary-adrenal (HPA) axis. It gives signals for the central nervous system to release a mix of hormones and changes the whole body to a different mode so it can deal with difficulties. The longer the stressful event lasts, the longer this “emergency mode” is active. It is usually related to the increase of cortisol – a hormone that is important in terms of a proper reaction to stress but can also cause some unpleasant or even harmful effects, especially when its level is elevated for a longer time. The HPA axis can be regulated by many neurotransmitters but one of them is especially important as it can inhibit this system. It is gamma-aminobutyric acid (GABA) that, in general terms, helps to calm down in difficult situations. All ingredients that can be found in our formula support the activity of GABA in every aspect of neuronal activity. Brahmi and Lemon balm increase the level of a GAD enzyme that acts as a catalyst in the production of GABA. L-theanine also stimulates the activity of this neurotransmitter (even by up to 20%), however, the exact mechanism of this effect is still unclear. Magnolia increases the density of GABA receptors. Additionally, the active substances contained in this herb act as positive allosteric modulators of benzodiazepine receptors. Those types of receptors are actually a part of GABA-A receptors. Their activation (induced by magnolia) stimulates GABA activity. Thanks to that, the molecules of this neurotransmitter can affect their target neurons. Lemon balm inhibits the enzyme that breaks down GABA so this neurotransmitter can remain in the synapses and affect the cells for a longer time. All in all, the herbs that are included in our recipe make GABA production more efficient, induce stronger effects of this neurotransmitter and slow down the breakdown of its molecule. Thanks to that, the brain – but in a big picture the whole body – can be more stress resilient and stay calm.

Improves mental well-being: GABA is one of the key compounds involved in stress resilience. But there are also other neurotransmitters necessary for psychological comfort. Serotonin is commonly known as a “happiness hormone” for a specific reason – it simply induces a sense of joy and supports a good mood. Dopamine, on the other hand, is released during the activation of the reward system and is related to pleasure, satisfaction and motivation. The ingredients found in our natural formula can influence those parts of neuronal activity. Brahmi increases the expression of genes that code tryptophan hydroxylase – an enzyme that takes part in serotonin production. The active compounds of magnolia bind to the receptors of serotonin and dopamine. Scientists suggest that this is the mechanism through which they can regulate the activity of those neurotransmitters. Brahmi also has a regulatory function. It has been proven that it helps to maintain the amount of serotonin and dopamine at a proper level, preventing sudden changes caused by stress. L-theanine improves the activity of GABA but it is not the sole property of this compound. It can also promote brain waves (cycles of bioelectrical brain activity) with the alpha frequency. Their presence usually indicates that the brain is relaxed but stays focused and aware. All these effects make our formula a solid and long-lasting support for mental comfort.

Supports the brain: Stress usually has a negative impact on one’s mood but there might be even more issues. Under stress some people experience attention problems and less clarity of mind. Generally, the spheres of the nervous system that are responsible for cognitive functions might be disrupted. All the ingredients contained in our formula will provide support in that regard as they are able to improve stress resilience by stimulating the activity of GABA. But their influence on cognitive activity is much broader. Acetylcholine is particularly important here as this substance acts as a neurotransmitter that determines the efficiency of data processing within the brain and facilitates consolidation of memory. Brahmi stimulates the activity of choline acetyltransferase – an enzyme that is a catalyst in the production of acetylcholine. Magnolia stimulates the release of this neurotransmitter to the synapses and facilitates binding its molecules to the receptors. Brahmi, Magnolia and Lemon balm are acetylcholinesterase inhibitors which basically means that they reduce the activity of an enzyme that breaks down acetylcholine molecules. So, when this neurotransmitter is produced in greater amounts, gets quickly released to the synapses and breaks down at a slower rate, it can affect the cells more effectively – providing positive effects on memory and attention. But going back to stress, it is worth pointing out that nervous tension can even physically damage the nerve cells. L-theanine, Lemon balm and Brahmi might counteract this effect because they stimulate neurotrophic factors that are necessary for neurogenesis – the production of new neurons. They are also crucial for the cells to create new connections which is particularly important for memory and learning abilities. Additionally, L-theanine will help to get into a proper mood. This natural compound from green tea stimulates alpha brain waves (8-13 Hz). They are typical for the mental state known as “relaxed awareness” that is great for learning. Those stress-mitigating properties will certainly reduce the negative impact of stress and help to process information more efficiently.

COMFORTIL™ Original formula specification

PRODUCT TYPE:
  • herbal preparation in gelatin capsules
TYPICAL DOSING:
  • 2 capsules daily or as advised by a healthcare professional
INGREDIENTS:
[800 mg / 2 caps.]
PACKAGING:
  • airtight PET bottle 100 ml / 120 ml
INTENDED USE:
  • nutrition, neuroregulation, clinical research, natural medicine
LEGAL STATUS:
  • product admitted to trading in the EU and the US

COMFORTIL™ Original formula usage

CAPSULES PER SERVING:
  • 2
SERVINGS PER DAY:
  • 1 – 2
BEST ABSORPTION:
  • with food
WHEN TO USE:
  • during the day / in the evening
OPTIMAL CYCLE DURATION:
  • 6 weeks of using – 2 weeks of break

COMFORTIL™ Original formula stacking

To increase stress resilience:
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TESTOGEN™ Original
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ASHWAGANDHA + SHILAJIT
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REISHI + LION’S MANE
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To improve general mood:
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MEMOSTIM™ Original
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NEURIDINE™ Original
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ADAPTONIC™ ORIGINAL
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To support a good condition of the brain:
MEMOSTIM™ Original
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NEURIDINE™ Original
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RELATONIC™ ORIGINAL
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NOOPEPTIL™ Original
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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.