Supports the functioning of the liver: Research evidence shows that sylimarin plays a role in maintaining the homeostasis of the liver cells. In other words, it keeps their inner environment stable by preventing toxins from entering. What is more, it stimulates their natural repair processes. Berberine also exhibits neuroprotective properties. Specifically, it prevents the cells of this organ from damage that can be a result of toxic substances, including ethyl alcohol. Additionally, it lowers the intensity of hepatic gluconeogenesis and improves insulin signaling. Last but not least, both herbal extracts prevent the fibrosis of this organ by limiting the secretion of collagen and similar proteins within its tissues.

Controls body mass: It has been proven that berberine helps to lose weight. This is because it limits the production of adipose tissue and reduces the level of leptin – a hormone related to the sensation of hunger. During clinical trials, it has been shown that it allows to significantly reduce the value of BMI even without the use of additional diet or exercise. Together with sylimarin, it regulates the blood glucose level preventing the episodes of binge eating. The supplementation of berberine and sylimarin is particularly recommended to those people who find it hard to control their body weight due to metabolic disorders.

Regulates the level of cholesterol: Both berberine and sylimarin efficiently lower the blood level of cholesterol, particularly its “bad” fraction LDL. The results of clinical tests show that the first ingredient can reduce the amount of LDL even by 25%. This is possible thanks to several mechanisms that involve, among others, LDL receptors to capture these molecules from the blood. Additionally, berberine prevents the formation of foam cells that are involved in the development of atherosclerotic plaques. Sylimarin, on the other hand, lowers the oxygenation of lipids and the synthesis of cholesterol. What is more, it alters the proportion of its fraction in favor of ‘good’ HDL cholesterol form. Taken together, these properties make berberine and sylimarin an excellent support to the cardiovascular system.