Alpha-GPC is the most efficient and exceptionally absorbable source of choline. It supports the central nervous system in production of neurotransmitters – primarily acetylcholine. Alpha-GPC supplementation brings improvement of cognitive functions, including memory and attention. It also supports physical performance and regeneration of the body by stimulating growth hormone release.

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Alpha-GPC 50% | AlphaCholine™

Properties: Alpha-GPC (choline alphoscerate) is the most efficient source of choline. When administered orally, it is completely absorbed in the digestive tract and easily crosses the blood-brain barrier. Due to that reason, its effects can be felt shortly after administration. Alpha-GPC works twofold. Firstly, it supports concentration and makes it easier to acquire new information, due to its direct effect on the cholinergic system. Secondly, it optimizes the general functioning of the central nervous system by indirectly regulating other neurotransmitter systems. Thus, benefits of Alpha-GPC supplementation include higher motivation, more energy, and better mood. Moreover, choline alphoscerate has an influence on muscular activity, and that is why it is so popular among bodybuilders. When it is supplemented before a work-out, it strengthens muscle’s efficacy and increases the release of growth hormone.

Occurrence: Alpha-GPC is naturally present in the nervous tissue of the human body. It can also be found in food. Animal products that contain alpha-GPC include: milk, yoghurt, eggs, chicken (breast and liver), Atlantic cod, and salmon. Alphoscerate choline is also present in plant-based products such as: wheat products, oatmeals, oranges, strawberries, broccoli, courgettes, sweet potatoes, and bananas. It can also be synthesized from phosphatidylcholine or from the extract of soy lecithin – a mixture of phospholipids and sterols obtained from soybeans (Glycine max).

Biochemistry: Alpha-GPC (choline alphoscerate, alpha-glycerophosphocholine) is an organic chemical compound classified as a phospholipid. It is quickly and completely absorbed from the digestive tract. Furthermore, it is exceptionally water-soluble, which increases its bioavailability. In contrast to choline, it can quickly cross the blood-brain barrier. As a rich source of choline, it is a precursor of acetylcholine – an important excitatory neurotransmitter. What is more, Alpha-GPC supports the production of phosphatidylcholine – a phospholipid necessary to build cellular membranes in the brain, as well as in the whole body.

Fun fact: Alpha-GPC is one of the three phospholipid compounds available on the market that contain choline. The other two are CDP-choline and phosphatidylcholine. Alpha-GPC is the strongest among them, as it contains around 40% of pure choline per molecule. In comparison, the amount of choline in CDP-choline is roughly 18,5%. Such a high level of choline provides quick influence on the cholinergic system. Therefore, alpha-GPC is often used acutely, in order to support both the mind and the body. It can be supplemented right before a training to increase the secretion of growth hormone, thus enhancing the training results.

Alpha-GPC 50% | AlphaCholine™ benefits

Supports the brain condition: The results of multiple independent research studies confirm that choline alphoscerate can benefit the health and functioning of the central nervous system. It has been proven that it regulates the production and secretion of neurotransmitters such as dopamine, serotonin, or GABA. Their balanced activity is crucial for proper brain functioning. There is also evidence that Alpha-GPC optimizes the blood flow in blood vessels of the central nervous system. Due to that effect, neurons receive higher amounts of oxygen and nutrition, which improves their efficiency.

Improves memory and concentration: Acetylcholine is a neurotransmitter responsible for all major steps of information processing: acquisition, remembering, and recalling. Alpha-GPC is a rich source of choline, which is crucial for acetylcholine production. It has been proven that supplementation of Alpha-GPC results in the increase of cholinergic activity in the brain’s structures responsible for memory and concentration. Thus, its observable effects include significant increase of cognitive capacities as well as better learning outcomes.

Supports positive mood: The results of scientific studies show that alpha-GPC influences metabolism of neurotransmitters that support mood regulation such as dopamine, serotonin, and GABA. Dopamine is released during the stimulation of the so-called “reward-system”. Its higher activity results in better motivation and more satisfaction. Serotonin is often dubbed as “the happiness hormone”, because it is responsible for psychological wellbeing. GABA, on the other hand, supports coping with stress and stabilizes the mood. Their combined, optimal functioning is thus extremely important for our mental well-being.

Supports physical fitness: Alpha-GPC is popular among sportsmen and bodybuilders. Many scientific studies confirm that its supplementation is beneficial for  physical fitness in young and healthy participants. Administration of Alpha-GPC before a workout might increase the strength of muscles during exercise. It has also been proven that this compound stimulates secretion of growth hormone. Therefore, it can enhance the regeneration of muscles, even after an exhausting training.

Alpha-GPC 50% | AlphaCholine™ specification

PRODUCT TYPE:
  • powdered raw ingredient
STANDARDIZATION:
  • Alpha-GPC non-hygroscopic complex (>50%)
MEASURING TOOL:
  • 1.00 ml PET spoon containing 600 mg of Alpha-GPC (depending on the batch)
PACKAGING:
  • airtight ALU-PET foil bag with a desiccant packet
INTENDED USE:
  • nutrition
  • neuroregulation
  • natural medicine
  • product manufacturing
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

Alpha-GPC 50% | AlphaCholine™ usage

TYPICAL SERVING:
  • 400 – 800 mg
SERVINGS PER DAY:
  • 1 – 3
BEST ABSORPTION:
  • without food
WHEN TO USE:
  • during the day
OPTIMAL CYCLE:
  • 6 weeks of using – 2 weeks of break

Alpha-GPC 50% | AlphaCholine™ stacking

To support the brain:
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Uridine | PharmaUridine™
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Huperzine A 1% | Huperzia serrata
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Pyritinol | NeuroPyridoxine™
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Vinpocetine extract 99% | Vinca minor
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Sulbutiamine | NeuroThiamine™
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Inositol | Myo-inositol
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Black Ant extract 20:1 | Polyrhachis vicina
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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.