Alpha-lipoic acid (ALA) is a natural compound from the class of carboxylic acids. It supports the efficacy of any slimming and detoxifying diet. Additionally, it improves metabolism and stimulates production of glutathione in the liver. Therefore, it helps to maintain the optimal body weight, better intellectual performance and clarity of mind for years.

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ALA | Alpha-lipoic acid

Properties: Alpha-lipoic acid is a compound that naturally occurs in the human organism. It plays an important role in the metabolic processes that transform food into energy. Moreover, it can bind heavy metals into chelates — complex compounds that are easily expelled from the body. Thanks to that, ALA is involved in the detoxification of the organism. 

Scientific research supports the claim that ALA supplementation can reduce appetite and therefore lower the calories intake. Given its properties, alpha-lipoic acid provides powerful support to any slimming and detoxifying diet regime. Importantly, ALA can increase the activity of telomerase — an enzyme crucial in the cellular division process. Quick and efficient cell division is a marker of the organism’s youth. Therefore, alpha-lipoic acid may delay the aging-related decrements.

With strong antioxidant properties alpha-lipoic acid has the ability to protect the bodily tissue from free radicals and chelate heavy metals. Moreover, ALA supports the activity of other antioxidants such as vitamins C and E, glutathione, or Q10 coenzyme. It also has anti-inflammatory and regenerative properties, as it can reduce the sun burns caused by UVB radiation. Its additional advantage is the efficiency with which it penetrates the stratum corneum and enters deeper layers of the skin. What is more, it increases the bioavailability of vitamin A, tightens pores and lightens discolorations. For those reasons ALA is widely used in cosmetics recommended for mature, acne-prone and UV-sensitive complexions.

Occurrence: Alpha-lipoic acid is naturally present in the human organism. It is synthesized in the mitochondria, particularly in the liver. ALA can also be found in food. Animal products rich in alpha-lipoic acid include red meat and offals such as heart, kidneys and liver. Some plants, particularly broccoli, Brussel sprouts, spinach, green peas and tomatoes also contain ALA.

Biochemistry: Alpha-lipoic acid (1,2-Dithiolane-3-pentanoic acid, thioacetic acid) is an organic chemical compound that belongs to the group of carboxylic acids, specifically to saturated fatty acids. It is water and oil soluble. Its bioavailability in the organisms reaches about 30%. In the organism it plays the role of cofactor —  a compound necessary for proper functioning of enzymes, which catalyze metabolic processes that are responsible for the transformation of food into energy. Thioacetic acid is also a powerful antioxidant. Moreover, it has a unique capability to chelate heavy metals and neutralize free radicals that are subsequently removed from the organism.

Fun fact: Alpha-lipoic acid — ALA — occurs in the species of yeasts Saccharomyces cerevisiae that are used in the breweries to produce upper fermentation beers called “ALE”. These yeasts cannot transform certain sugars and that is why “ALE” beers are characterized by more complex taste and aroma than lagers (lower fermentation beers).

ALA | Alpha-lipoic acid benefits

Supports detoxification of the organism: Scientific evidence from in vitro and animal experimentation provides support for the claims that alpha-lipoic acid can be helpful in expelling certain toxic or harmful substances from the organism, e.g. free radicals. ALA reduces their amount in the organism twofold: it neutralizes them and it stimulates the production of glutathione — one of the strongest antioxidants secreted in the human body. ALA also has the ability to chelate heavy metals such as lead, mercury or cadmium, thereby facilitating the process of their removal from the body.

Helps with body weight reduction: Alpha-lipoic acid efficiently supports meeting weight loss goals by reducing the appetite. The results of scientific studies show that ALA supplementation can decrease the food intake even by 30%. Moreover, this compound intensifies the metabolism, thereby enhancing the transformation of food into energy. It also speeds up fat burning and decreases the amount of glucose in blood, stimulating its conversion into glycogen which temporarily stores energy. Clinical trials confirmed that alpha-lipoic acid supplementation can increase the efficacy of slimming diets.

Supports the nervous system: Results of multiple scientific studies imply that alpha-lipoic acid has a beneficial influence on the functioning and wellbeing of the nervous system. Essentially, its antioxidant properties help to reduce the neuronal oxidative stress. ALA is also involved in the regulation of neurotransmitter secretion, including these relevant for concentration and memory. For instance, alpha-lipoic acid supplementation was shown to increase the dopamine level by 9%. Additionally, ALA improves the condition of myelin sheaths responsible for protection and nutrition of the neural cells.

Improves general health: Several scientific studies suggest that alpha-lipoic acid may slow down the aging process. It has been demonstrated that this compound stimulates the mitochondrial activity and cellular energy production — the process, which becomes progressively less effective as we age. Furthermore, ALA increases the activity of telomerase – the enzyme that repairs DNA strings shortening after each cellular division. That way, the amount of available divisions is increased and as a result the organism has a better potential to regenerate its cells. In addition, alpha-lipoic acid plays an important role in reduction of cholesterol levels (particularly the amounts of its “bad” fraction – LDL) and thereby is essential in the prevention of arteriosclerosis. Because of that, the supplementation of ALA improves the general health of the whole organism.

ALA | Alpha-lipoic acid specification

PRODUCT TYPE:
  • powdered raw ingredient
STANDARDIZATION:
  • pure RS-alpha-lipoic acid (>99%)
MEASURING TOOL:
  • 0.50 ml PET spoon containing 250 – 300 mg of ALA (depending on the batch)
PACKAGING:
  • airtight ALU-PET foil bag with a desiccant packet
INTENDED USE:
  • nutrition
  • neuroregulation
  • natural medicine
  • product manufacturing
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

ALA | Alpha-lipoic acid usage

TYPICAL SERVING:
  • 300 – 600 mg
SERVINGS PER DAY:
  • 1 – 2
BEST ABSORPTION:
  • with food
WHEN TO USE:
  • during the day
OPTIMAL CYCLE:
  • 6 weeks of using – 2 weeks of break

ALA | Alpha-lipoic acid stacking

To support detoxification:
NAC | NeuroCysteine™
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SAM-e | S-adenosyl methionine
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TMG | Betaine anhydrous
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Silymarin extract 80% | Silybum marianum
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To facilitate weight loss:
ALCAR | Acetyl-L-Carnitine
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Caffeine | Anhydrous Caffeine
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Green Coffee extract 50% | CoffeeGreen
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EGCG extract 50% | Camellia sinensis
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To support the nervous system:
ALCAR | Acetyl-L-Carnitine
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5,0045,00

Coenzyme Q10 | Ubiquinone
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Creatine HCL | PharmaCreatine™
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Curcumin extract 95% | Curcuma longa
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To improve vitality:
Black Rice extract 25% | Oryza sativa
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Coenzyme Q10 | Ubiquinone
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Shilajit extract 20:1 | Asphaltum punjabianum
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7,0075,00

Curcumin extract 95% | Curcuma longa
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9,00108,00

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.