5-HTP Griffonia simplicifolia
5-HTP Griffonia simplicifolia
5-HTP Griffonia simplicifolia
5-HTP Griffonia simplicifolia
5-HTP Griffonia simplicifolia
5-HTP Griffonia simplicifolia

5-HTP quickly and naturally increases the amount of serotonin in the brain. Therefore, it makes falling asleep easier, helps to normalize the circadian rhythm, and also increases the efficacy of nocturnal regeneration. Moreover, supplementation with 5-HTP supports a positive mood and decreases the appetite which makes weight loss definitely easier.

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5-HTP extract 99% | Griffonia simplicifolia

Properties: 5-HTP (5-hydroxytryptophan) is an amino acid produced in the human body from L-tryptophan. The main causes of 5-HTP deficits are diet poor in L-tryptophan or metabolic impairments in the synthesis of 5-HTP. Therefore, its direct supplementation becomes more and more popular.

Usually, the first noticeable effect of 5-HTP supplementation is the impression of waking up more refreshed without prolonging the sleep duration. Instead, the quality of sleeping is simply better. 5-HTP reduces the amount of insomnia-related stress, thereby making falling asleep less challenging. This effect alone improves the mood the following day. 

There are even more beneficial effects of 5-HTP. It produces serotonin, also known as the “happiness hormone”, which is responsible for the sense of inner balance. When the organism has enough raw material to synthesise serotonin, achieving relaxation becomes much easier. Importantly, 5-HTP influences serotonin release so it has the ability to reduce sugar craving.

Occurrence: The seeds of an African black bean called Griffonia simplicifolia contain between 6% to 14% of 5-HTP and as such are its main source. Additionally, this amino acid can be obtained from the fruit bodies of edible mushrooms: shitake (Lentinula edodes), parasol mushroom (Macrolepiota procera), and bovine bolete (Suillus bovinus) – either raw or processed.

Biochemistry: 5-HTP (5-hydroxytryptophan) is an organic chemical compound naturally present in the human body. It is an amino acid derived from tryptophan, which is a direct precursor of serotonin and an indirect precursor of melatonin. Partially transformed to serotonin in the human digestive tract it easily crosses the blood-brain barrier and thereby effectively acts on the central nervous system.

Fun fact: The African black bean is a plant traditionally used by the indigenous inhabitants of Western and Central Africa as a remedium for mood disorders. For that reason, this plant captured the attention of scientists who isolated 5-hydroxytryptophan from its seeds. Currently, 5-HTP is one of the most popular dietary supplements in the US.

5-HTP extract 99% | Griffonia simplicifolia benefits

Improves general mood: 5-HTP is a precursor of serotonin — the neurotransmitter crucial for achieving and maintaining a positive attitude. Its levels are sometimes decreased due to an impairment of tryptophan metabolism. Supplementation of 5-HTP can naturally counteract that impairment and thereby normalize the production of serotonin. Even if the tryptophan metabolism is functioning properly, delivery of 5-HTP as an additional material for serotonin production is a safe and effective mood enhancement method, as it does not impact the processes normally occurring in the brain.

Improves the quality of sleep: 5-HTP is an indirect precursor of melatonin, a hormone responsible for circadian rhythm regulation. Melatonin is secreted after sunset. That is a signal for the organism to start preparing for sleep. Supplementation of 5-HTP, especially before sleep, helps to increase melatonin activity and normalizes the circadian rhythm. Apart from that, this amino acid prolongs the REM phase of sleep during which the dreams occur.

Supports weight loss: One of the main functions of serotonin is the control of appetite. For instance, this neurotransmitter is responsible for the feeling of satiety after a meal. Sudden drops of its level are associated with episodes of binge eating and sugar craving. Through 5-HTP supplementation the level of serotonin becomes normalized, which supports the regulation of appetite, decreases food craving, and reduces calories intake, especially in the form of carbohydrates.

Improves stress resilience: The proper activity of serotonin is key not only for a positive attitude. This “happiness hormone” is also very important in terms of stress resilience and the ability to deal with difficult situations. When this neurotransmitter is in shortage, the organism is more vulnerable to stress – both physical and psychological. Because of that we might experience trouble with sleeping and the regeneration abilities of the body might drop. In these circumstances stressful stimuli affect us much stronger. Delivery of 5-HTP – the raw material needed to produce serotonin – helps to prevent an uncontrolled decrease of serotonin secretion. Therefore, it’s easier for us to achieve mental comfort and deal with stressful everyday challenges.

5-HTP extract 99% | Griffonia simplicifolia specification

PRODUCT TYPE:
  • powdered herbal extract
STANDARDIZATION:
  • Griffonia simplicifolia seed extract (>99% of 5-HTP)
MEASURING TOOL:
  • 0.30 ml stainless steel spoon containing 150 – 250 mg of extract (depending on the batch)
PACKAGING:
  • airtight ALU-PET foil bag
  • desiccant packet Tyvek™ Microbag
INTENDED USE:
  • nutrition
  • neuroregulation
  • natural medicine
  • product manufacturing
  • research
LEGAL STATUS:
  • ingredient admitted to trading in the EU and the US

5-HTP extract 99% | Griffonia simplicifolia usage

TYPICAL SERVING:
  • 100 – 200 mg
SERVINGS PER DAY:
  • 1 – 2
BEST ABSORPTION:
  • without food
WHEN TO USE:
  • before bedtime
OPTIMAL CYCLE:
  • 4 weeks of using – 2 weeks of break
NOTES:
  • 5-HTP can be taken together with EGCG to improve production of serotonin in the brain

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The above information about products should be considered a historical and scientific facts, not a recommendation on how to use a specific substance. Dietary supplements should not be treated as an alternative to a healthy lifestyle and balanced diet. The above information is not medical advice. Every use of a dietary supplement or herbal/nootropic compound should be consulted with a doctor or a specialist. Dietary supplements as well as nootropic and herbal compounds should not be mixed with medication. Our products should not be used by breastfeeding women and by the people under the age of 18.